Isihloko
Ukugcinwa kwe-methylene blue nesikhathi sokufaneleka: funda ilebula yomkhiqizo
I-methylene blue ayinaso isikhathi esisodwa sokufaneleka esisebenza kuyo yonke imikhiqizo. Impushana evaliwe, ingxube elungisiwe enamanzi, nomuthi womjovo womthamo owodwa kuyimikhiqizo ehlukene. Izinsuku zayo zincike entweni esetshenzisiwe, ekwakhiweni kwengxube, ekupakishweni, ezimweni zokugcina, nasebufakazini obusekela ukuzinza kwayo.
Qala ngesiqukathi sakho. Thola inombolo yeqoqo laso, imiyalelo yokugcina, nosuku lokuphelelwa yisikhathi noma lokugcina umkhiqizo ungcono ngaphambi kwalo. Bese uhlola ukuthi ikhona yini imiyalelo ehlukile yokuvula noma yokulungisa. Isitatimende esiku-inthanethi esithi “i-methylene blue ihlala iminyaka” asikwazi ukuqinisekisa ukuthi lelo bhodlela elithile lizohlala lifanele isikhathi esingakanani.
Lokho usuku olukuchaza ngempela
Mayelana nemithi, i-FDA ichaza ukuthi izinsuku zokuphelelwa yisikhathi zibonisa ukuzinza okuqinisekisiwe ngaphansi kwezimo zokugcina ezibhalwe kulebula. Ukuzinza kuhlanganisa ukugcina amandla, ikhwalithi, nobumsulwa obudingekayo. Usuku luhlobene nobufakazi obuphathelene nomkhiqizo, hhayi nje negama lesithako sawo esiyinhloko.
Izinsuku ezihlukene ziphendula imibuzo ehlukene:
- Usuku lokukhiqizwa noma lokukhululwa: lapho kwenzeka isenzakalo sokukhiqiza noma kwenziwa isinqumo sokukhulula iqoqo. Lokhu akulona ngokuzenzakalela usuku lokugcina lokusebenzisa.
- Usuku lokuphelelwa yisikhathi noma lokugcina lokusebenzisa: ukuphela kwesikhathi esabelwe umkhiqizo othile ngaphansi kwezimo zawo ezishiwo.
- Usuku lokuphinda kuhlolwe: isikhathi lapho into idinga ukuhlolwa kabusha ngendlela efanele ngokwezidingo ezibekiwe zayo. Akuyona imvume yokwelula isikhathi sokuyisebenzisa ngokuhlola umbala.
- Umkhawulo wangemva kokuvula noma wokulungisa: imiyalelo esebenza lapho iphakethe langempela selivuliwe noma ukwakheka kwengxube kushintshiwe. Engxubeni elungisiwe enikezwe ekhemisi, lokhu kungavela njengosuku okungafanele isetshenziswe ngemva kwalo kulebula yekhemisi.
Umbhalo wakwa-Merck wokubeka izinsuku emikhiqizweni uhlukanisa izinsuku zokukhululwa, zokuphelelwa yisikhathi nezokuphinda kuhlolwe. Lo mehluko ubalulekile lapho ufunda isitifiketi sesithako. Usuku lokuphinda kuhlolwe impushana ye-methylene blue aluqinisekisi usuku lokuphelelwa yisikhathi kwengxube ewuketshezi eyenziwe ngayo kamuva. Nosuku lomkhiqizo ongakavulwa aluphenduli ngokuzenzakalela yonke imibuzo ngesiqukathi esivuliwe.
Ingabe i-methylene blue idinga ukugcinwa esiqandisini?
Ungayigcini esiqandisini ngokuzenzakalela. Landela imiyalelo yezinga lokushisa yomkhiqizo othile onawo.
Imihlahlandlela ye-Blupreme yokugcina ingxube ewuketshezi ithi kufanele igcinwe ime iqonde, ivikelwe ekukhanyeni, futhi ibe sezingeni lokushisa elingaphansi kuka-25 °C. Ithi ukugcinwa esiqandisini akudingekile futhi ingxube akufanele iqandiswe. Gcina ibhodlela livaleke kahle futhi ulandele usuku lokugcina umkhiqizo ungcono ngaphambi kwalo olubhalwe ephaketheni lawo. Imibuzo evame ukubuzwa ayisho isikhathi esihlukile sangemva kokuvula okwamanje; lokho kungashiwo akubona ubufakazi benani lezinyanga elisanda kuqanjwa.
Umkhiqizo ohlukile unikeza isibonelo esiwusizo sokuqhathanisa. Ilebula yomuthi womjovo i-PROVAYBLUE ibeka izinga lokushisa elingu-20–25 °C, futhi ivumela ukuphambuka kuya ku-15–30 °C. Ikwenqabela ngokucacile ukugcinwa esiqandisini nokuqandisa, idinga iphakethe langempela ukuze ivikele ekukhanyeni, futhi iyalela ukulahlwa kokusele okungasetshenziswanga ezitsheni zayo zomthamo owodwa. Le miyalelo ingeyalowo muthi. Ayiyona imiyalelo yokugcina noma yokusebenzisa kabusha ibhodlela elineconsi elidayiswa ezitolo.
Ngakho-ke, umthetho othi “uma kubanda kakhulu kufanele kube ngcono” awuthembekile. Uma umkhiqizo uqanda ngesikhathi uthuthwa noma ibhodlela lichitha amahora emotweni eshisayo, bhala phansi okwenzekile bese ubuza umkhiqizi ukuthi umkhiqizo usafanele yini. Ukuwubuyisela ezingeni lokushisa elinconyiwe akuqinisekisi ukuthi lokho kuchayeka akuwulimazanga.
Impushana idinga imiyalelo yayo
Ukugcina impushana akufani nje nokugcina ingxube ewuketshezi ekhishwe amanzi. Funda iphakethe neshidi ledatha yokuphepha lento oyinikeziwe. Imiyalelo yomkhiqizo oyimpushana we-Blupreme idinga iphakethe elivalwe ngokuqinile, izimo ezomile, nokuvikelwa ekukhanyeni.
Njengesinye isibonelo esiqondene nomkhiqizo othile, imiyalelo ye-methylene blue i-Certistain yakwa-Merck ibeka izinga elingu-5–30 °C laleyo khemikhali eyomile esetshenziswa ekuhloleni ngesibonakhulu. Ivumela ukuthi okuqukethwe okunikeziwe kusetshenziswe kuze kufike usuku lokuphelelwa yisikhathi olushiwo ngemva kokuvula kokuqala, uma lezo zimo zigcinwa futhi ibhodlela lihlala livalwe ngokuqinile. Lokhu akubeki usuku olufanayo engxubeni ewuketshezi yokufaka umbala elungiswe ngempushana elabhorethri.
Ngaphambi kokuthenga iphakethe elikhulu, hlola ukuthi ungakwazi yini ukulisebenzisa phakathi nesikhathi salo esibhalwe emibhalweni futhi uligcine livaleke kahle phakathi kokusetshenziswa. Umhlahlandlela wokuthenga impushana uhlanganisa imibuzo yezinga lekhwalithi, yobukhulu bephakethe, neyemibhalo.
Uhlu lokuhlola ukugcinwa olusekelwe kulebula
Sebenzisa leli thebula unesiqukathi nombhalo weqoqo ohambisana naso phambi kwakho. Kopisha imiyalelo yangempela kukholomu yokugcina. Inkambu engenalutho iveza umbuzo okufanele uxazululwe, hhayi isimo okufanele usiqagele.
| Okufanele kuhlolwe | Ingxube ewuketshezi elungisiwe | Impushana enikeziwe | Okubhaliwe ngalo mkhiqizo |
|---|---|---|---|
| Ukuhlonzwa | Umkhiqizo othile, ukugxila, ukusetshenziswa okuhlosiwe | Umkhiqizo othile, izinga lekhwalithi, isimo onikezwe ukuso | Umkhiqizo: ______ |
| Iqoqo | Qhathanisa ibhodlela nemibhalo | Qhathanisa iphakethe nesitifiketi | Iqoqo: ______ |
| Uhlobo losuku | Ukuphelelwa yisikhathi/usuku lokugcina umkhiqizo ungcono ngaphambi kwalo nanoma yiluphi usuku lokukhishwa ekhemisi | Ukuphelelwa yisikhathi noma ukuphinda kuhlolwe, hhayi nje usuku lokukhululwa | Uhlobo/usuku: ______ |
| Izinga lokushisa | Kopisha ububanzi nemiyalelo yokuqandisa/yokugcina esiqandisini | Kopisha ububanzi obuqondene nempushana | Izimo: ______ |
| Ukukhanya nomswakama | Kopisha izidingo zokuvikela ekukhanyeni | Kopisha izidingo zokuvikela ekukhanyeni nezokugcina komile | Indawo: ______ |
| Ukuvalwa | Ibhodlela langempela, isivalo, nanoma yiliphi ibhokisi elidingekayo | Iphakethe langempela nokuvalwa kabusha okusebenzayo | Ukuvalwa kuhloliwe: ______ |
| Ngemva kokuvula | Bhala usuku lokuvula nomkhawulo oshiwo wokusebenzisa | Hlola ukuthi ukuvula kuyasishintsha yini isikhathi esishiwo | Kuvulwe/umkhawulo: ______ |
| Kuhlanjululwe noma kulungisiwe | Thola imiyalelo yokwakheka kwengxube okushintshiwe | Ungadluliseli izinsuku zempushana engxubeni entsha ewuketshezi | Umbhalo osebenzayo: ______ |
| Isigameko ngesikhathi sokugcina | Qaphela ukushisa, ukuqanda, ukuvuza, noma ukukhathazeka ngokungcoliswa | Qaphela umswakama, iphakethe elonakele, noma ukuphambuka ezimweni zokugcina | Isigameko/isinyathelo: ______ |
Kungani isiqukathi nokuvikelwa ekukhanyeni kubalulekile
Gcina ilebula nephakethe langempela ngaphandle uma imiyalelo yomkhiqizo idinga okuhlukile. Ibhodlela elifakwa esikhundleni singahluka ekuvikeleni ekukhanyeni, ekuvalekeni, nasekuhambisaneni kwezinto elenziwe ngazo nomkhiqizo. Ingxoxo ye-FDA yokuhlola ukuzinza iveza umehluko ekwakhiweni kwengxube naseziqukathini nasezivalweni zazo njengezici ezithinta ukubekwa kwezinsuku zomkhiqizo.
Ibhodlela elinombala onsundu ophuzi alenzi ukukhanya kwelanga okuqondile kwamukeleke. Beka umkhiqizo endaweni ehambisana nemiyalelo yawo futhi egwema ukuchayeka ekushiseni okulindelekile. Uma ibhodlela elineconsi selivuliwe, gwema ukuthintisa ithuluzi lokukhipha amaconsi ezandleni, emlonyeni, noma ezindaweni zokusebenza; livale ngokushesha. Ungacabangi ukuthi umbala wedayi uqinisekisa ikhwalithi ngokuphathelene namagciwane nezinye izinto eziphilayo ezincane. Ingxoxo yobuchwepheshe yokukhanya, i-pH, izinto zokuncibilikisa, nokuzinza kwe-methylene blue ichaza ukuthi kungani ukuhlola nokwakheka kwezingxube kudinga izimo zakho.
Izinsuku ezingekho noma ukubukeka okushintshile
Uma ungakwazi ukuthola usuku, cela umphakeli ahlonze umbhalo weqoqo osebenzayo futhi achaze ukuthi umkhiqizo unosuku lokuphelelwa yisikhathi, lokuphinda kuhlolwe, noma omunye umkhawulo wokusebenzisa obhaliwe yini. Buza ngokwehlukile ngokusetshenziswa ngemva kokuvula. Incazelo yokwesekwa kwemikhiqizo yakwa-Sigma-Aldrich iphawula ngokucacile ukuthi ukungabikho kosuku lokuphelelwa yisikhathi noma lokuphinda kuhlolwe kungasho ukuthi idatha efanele yokuzinza ayanele ukubeka isikhathi sokufaneleka. Ukwaziswa okungekho akubona ubufakazi bokuzinza okungapheli.
Ukufiphala okungalindelekile, izinhlayiya, ukuvuza, noma isivalo esonakele kuyizizathu zokuyeka ukusebenzisa nokulandela imiyalelo yomkhiqizo. Ibhodlela elibukeka lijwayelekile aliphumeleli ekuhlolweni kokuphelelwa yisikhathi ngenxa yokubukeka kwalo. Ngakolunye uhlangothi, ukuba mnyama kukodwa kungabonisa ukuthi ingxube ewuketshezi egxile kakhulu imunca ukukhanya ngamandla kangakanani. Funda ngezingxube eziwuketshezi eziluhlaza, ezifiphele, noma ezicishe zibe mnyama kanye nezinto eziqinile eziphuma engxubeni namakristalu ngaphambi kokuthi uthi ukushintsha kokubukeka kubangelwa into eyodwa. Ungawushisisi, ungawuhlungi, futhi ungawuxubi kabusha umkhiqizo osolisayo ukuze uphinde ubukeke wamukeleka.