Isihloko
I-methylene blue nezemidlalo: indlela yokuhlola imithetho yokulwa nokudopha
I-methylene blue ayibaliwe ngegama layo oHlwini Lwezinto Ezivinjelwe lwe-WADA luka-2026 lwesiNgisi, olwahlolwa ngomhla ka-12 Septhemba 2026. Ukusesha elinye igama layo, elithi methylthioninium, nakho akutholanga okufanayo. Lokho okutholakele akuyona imvume yomuntu ngamunye yokusebenzisa umkhiqizo noma inqubo ethile. Ukuvunyelwa kudinga ukuhlola zonke izithako zomkhiqizo, indlela yokuwufaka emzimbeni, izigaba ezisebenzayo, nemithetho elawula umsubathi.
Ngakho impendulo ewusizo inezingxenye ezimbili: lokho imithombo esemthethweni ekushoyo namuhla, kanye nolwazi olusadingeka ngesimo sakho. Isimangalo somthengisi sokuthi umkhiqizo “uhambisana nemithetho ye-WADA” asikwazi ukunikeza ingxenye yesibili.
Qala ngomuthi oqondile nomdlalo
Ukusesha imithi kwe-Global DRO kudinga umdlalo nezwe okuthengwe kulo ngoba umkhiqizo wohlobo oluthile ungaba nezithako ezihlukile ezimakethe ezihlukahlukene. Qinisekisa ukuthi igama eliphelele lomkhiqizo, amandla awo, izithako ezisebenzayo, nendlela yokuwufaka emzimbeni kuyahambisana. Funda imibandela yomphumela yokusetshenziswa ngesikhathi somncintiswano nangaphandle komncintiswano. Gcina umphumela, kuhlanganise nosuku lwawo nenombolo yereferensi uma inikeziwe.
Isizindalwazi sihlanganisa imithi emazweni abambe iqhaza. Asinikezi imvume yezithasiselo, futhi imibandela yaso ichaza ukuthi kungase kusebenze nemikhawulo ehlukile yomfelandawonye noma yomcimbi omkhulu. Uma umuthi ungekho, buza inhlangano efanele yokulwa nokudopha kunokuthatha ukungatholakali komphumela njengemvume. Abasubathi ababamba iqhaza emidlalweni engaphezu kowodwa kudingeka bahlole umdlalo ngamunye.
Thumela isithombe selebula nombuzo oqondile. Umbuzo othi “Ngingayisebenzisa yini i-methylene blue?” ushiya ngaphandle ulwazi olungashintsha impendulo. Umbuzo owusizo kakhulu uthi: “Ngincintisana kulo mdlalo ngaphansi kwalo mfelandawonye. Nawu umkhiqizo, uhlu lwezithako, izwe okuthengwe kulo, indlela okuhloswe ukuwufaka ngayo emzimbeni, nokusetshenziswa kwezokwelapha okuhlongozwayo. Yimiphi imithetho nezidingo zokuthola ukukhululwa ezisebenzayo?”
Funda izigaba, hhayi nje inkomba yamagama elandelana ngokwezinhlamvu
UHlu lwe-WADA luqukethe izigaba ezibanzi nezibonelo ezingabali konke. Ukusesha igama akunakuqinisekisa ukuthi into ayingeni kunoma yisiphi isigaba. Ngokufanayo, ukukhangisa okukhuluma “nge-mitochondria” noma “ngomoya-mpilo” akusho ukuthi into ihlukaniswa njengelawula ukuguqulwa kwezinto emzimbeni noma njengendlela evinjelwe yokushintsha igazi. Xazulula ukungaqiniseki ngokuhlukaniswa kwayo nenhlangano yokulwa nokudopha enesibopho.
I-S0 iphathelene nezinto ezisebenza njengemithi ezingenayo imvume yamanje kahulumeni yokwelapha abantu futhi ezingachazwanga kwenye indawo oHlwini. Akukhona nje ukuhlola ukuthi ibhodlela elithengiswa esitolo linelebula yomuthi odinga incwadi kadokotela yini. I-methylene blue inomuthi ovunyelwe ukusetshenziswa kubantu, umjovo we-PROVAYBLUE wokwelapha i-methemoglobinemia etholakele. Lelo qiniso aliqinisekisi ukuthi olunye uhlobo lomkhiqizo, isithako esengeziwe, noma ukusetshenziswa okuhlongozwayo kuvumelekile.
Indlela ye-IV idinga ukuhlolwa ngokwayo
Ngaphansi kwe-M2.2, ukufakwa koketshezi nemijovo emthanjeni okungaphezu kuka-100 mL esikhathini samahora angu-12 sekukonke kuvinjelwe ngaso sonke isikhathi, ngaphandle kwezimo ezishiwo zokwelashwa okufanele esibhedlela, ukuhlinzwa, noma ukuhlolwa komtholampilo kokuthola isifo. Inothi lamanje le-USADA elichaza i-IV lichaza ukuthi lokhu kusebenza ngisho nasezithakweni ezivunyelwe. Isamba sihlanganisa ukufakwa okwenziwa izikhathi eziningi; akusona isilinganiso esivunyelwe esihlukile sesikhwama ngasinye noma somjovo ngamunye. Umkhawulo uphathelene nomthamo woketshezi, hhayi amamiligremu e-methylene blue, futhi awusona isincomo sokwelashwa.
Imihlahlandlela ye-WADA yodokotela mayelana ne-IV, inguqulo 8.1, ihlukanisa ukwelashwa esibhedlela nokwenziwa ehhovisi elijwayelekile lodokotela, egumbini lehhotela, ekhaya, etendeni lezokwelapha lomcimbi, noma emtholampilo we-IV ozimele. Ukuthi uchwepheshe wezokwelapha ufaka uketshezi akusho ngokuzenzakalelayo ukuthi kunokukhululwa emthethweni. Uma into efakwa ngokwayo ivinjelwe, ukukhululwa kwendlela yokuyifaka lapho isetshenziswa esibhedlela akususi isidingo se-TUE saleyo nto.
Uma ukwelashwa kuhleliwe, nikeza inhlangano yokulwa nokudopha imininingwane ephelele yenqubo. Uchwepheshe wezokwelapha kufanele abhale ukuxilongwa, izithako, umthamo ophelele woketshezi, izikhathi, indawo, nesizathu sezokwelapha. Incazelo yethu yemijovo ye-methylene blue nezingxube ze-IV ichaza ukuthi kungani ukufaneleka komkhiqizo ukujovwa nakho kuwumbuzo wezokwelapha ohlukile.
Esimweni esiphuthumayo, thola ukwelashwa okudingekayo kuqala. Yazisa inhlangano enesibopho ngemva kwalokho bese ugcina amarekhodi. Ukukhululwa kokusetshenziswa kokwelapha okunikezwa emuva kokwelashwa, noma i-TUE, kungase kutholakale ezimweni ezifanelekile; akunikezwa ngokuzenzakalelayo. Umhlahlandlela we-USADA nge-TUE uchaza ukuhlolwa kokuxilongwa, isidingo sokwelashwa, ezinye izindlela ezivunyelwe, nezidingo zokufaneleka ezisebenzayo.
Ibhodlela lingaletha inkinga ehlukile
Umkhiqizo oqukethe i-methylene blue ungase ube nezinye izithako ezisebenzayo. Isithasiselo singase sibe nezinto ezingcolisayo ezingashiwongo. Umhlahlandlela we-UK Anti-Doping ngezithasiselo uchaza isibopho esiqinile: abasubathi banesibopho sezinto ezivinjelwe ezisemizimbeni yabo, kuhlanganise nalezo ezingene bengahlosile. Ubuye usho ukuthi izinhlangano zokulwa nokudopha azivumeli noma zisekele imikhiqizo yezithasiselo.
Ukuhlolwa kwamaqoqo omkhiqizo kunganciphisa ubungozi bokungcoliswa, kodwa akunakuqinisekisa ukuvunyelwa. Umbiko wobumsulwa bamakhemikhali awukona ngokuzenzakalelayo ukuhlolwa kwezinto ezivinjelwe yimithetho yokulwa nokudopha. Hlola ukuthi yini eyahlolwa ngempela nokuthi iqoqo elahlolwa liyahambisana yini nebhodlela elithengiwe. Umhlahlandlela wokufunda isitifiketi sokuhlaziywa kwe-methylene blue uchaza lokho kuhlolwa kwemibhalo.
Uhlu lokuqinisekisa olunosuku
Imithombo esemthethweni yahlolwa: 12 Septhemba 2026. UHlu luka-2026 lwaqala ukusebenza ngomhla ka-1 Januwari 2026. Phinda uhlole lapho kushintsha imithetho, umkhiqizo, indlela yokuwufaka emzimbeni, umdlalo, noma umcimbi. Kopisha leli thebula erekhodini lakho bese ugcwalisa isikhala ngasinye ngomphumela nobufakazi.
| Ukuhlola | Umthombo osemthethweni nesinyathelo | Irekhodi lakho |
|---|---|---|
| 1. Imithetho elawulayo | Vula uHlu lwamanje lwe-WADA; qinisekisa uhlelo olusebenzayo nemithetho eyengeziwe yomfelandawonye noma yomcimbi wakho. | Umdlalo, umfelandawonye, umcimbi, uhlelo, usuku: ___ |
| 2. Umkhiqizo oqondile | Landela imiyalelo yokusesha ye-Global DRO; qinisekisa ukuthi izwe, umkhiqizo ophelele, izithako, nendlela yokuwufaka emzimbeni kuyahambisana. Dlulisela imiphumela engekho noma engaqondakali enhlanganweni enesibopho. | Umkhiqizo, iqoqo, ikhophi yelebula, umphumela/ireferensi: ___ |
| 3. Indlela | Sebenzisa incazelo esemthethweni ye-IV ukuhlola yonke inqubo nethimba elikwelaphayo. | Indlela yokufaka emzimbeni, umthamo, izikhathi, indawo, ukuhlolwa okubhaliwe: ___ |
| 4. Ukukhululwa | Landela inqubo yesiphathimandla esifanele; umhlahlandlela we-UKAD othi Search Check Apply ubonisa indlela yokuhlola ukuthi kufanele yini ufake isicelo, usifake nini, nokuthi usifaka kanjani nobufakazi bezokwelapha. | Isiphathimandla esinesibopho, isidingo, isinqumo, imibandela: ___ |
| 5. Ubufakazi obugciniwe | Gcina ilebula, umphumela wokusesha, amarekhodi ezokwelapha, nokuxhumana okubhaliwe. Qinisekisa nesiphathimandla sakho ukuthi umcimbi uyayemukela yini i-TUE esivele ikhona. | Indawo yefayela, ukwamukelwa, usuku lokuphelelwa yisikhathi/lokuhlola kabusha: ___ |
Umugqa ongakaxazululeki uwumbuzo okufanele uwuyise enhlanganweni enesibopho. Ithebula liqopha inqubo yokuqinisekisa; ukuligcwalisa akukhona ukukhululwa emthethweni noma imvume esemthethweni.
Ukuvunyelwa, ukusebenza kwezemidlalo, nokuphazamiseka kokuhlolwa kuyimibuzo ehlukile
Umphumela wokuhlola imithetho yokulwa nokudopha awuqinisekisi ukuthi i-methylene blue ithuthukisa ukukhuthazela, amandla, noma ukululama. Lezo zimangalo zidinga imiphumela efanele yokusebenza kwabantu kwezemidlalo, hhayi nje isiphetho esithathwe endleleni amakhemikhali asebenza ngayo emzimbeni. Umhlahlandlela wobufakazi bokuzivocavoca nokululama ubhekana nalowo mbuzo ohlukile.
Ukuphazamiseka kwezilinganiso zomtholampilo nakho kuhlukile. Ilebula ye-PROVAYBLUE ibhala ngezilinganiso ze-pulse oximeter ezibonisa amanani aphansi kunawangempela nangokuphazamiseka kokuhlolwa komchamo okusebenzisa izinkomba eziluhlaza okwesibhakabhaka, kuhlanganise nemicu yokuhlola i-leukocyte esterase. Lokhu okubonwe akufakazeli ukuthi kwenzekani ekuhlolweni okuthile kokulwa nokudopha futhi akunikezi ukukhululwa ekuhlolweni kokudopha. Tshela abasebenzi bezokwelapha ngokungena kwale nto emzimbeni ukuze bakwazi ukuhumusha izilinganiso; bheka i-methylene blue nokuphazamiseka kokuhlolwa kwaselabhorethri.
Ukufaneleka ngokwezokwelapha kuseyisinqumo esihlukile, kuhlanganise nokusebenzisana neminye imithi kanye nobungozi obuhlobene ne-G6PD obuchazwe kumhlahlandlela wokuphepha kwe-methylene blue. Nikeza kokubili uchwepheshe wezokwelapha okwelaphayo nenhlangano yokulwa nokudopha enesibopho ulwazi olufanayo nolunembile ngomkhiqizo nangokungena kwawo emzimbeni.