Chinyorwa
Kuchengetwa kwemethylene blue nenguva yainogara: verenga chinyorwa chiri pachigadzirwa
Methylene blue haina nguva imwe chete yainogara yakakodzera kushandiswa pazvigadzirwa zvose. Hupfu hwakavharwa, chinonyungudutswa chakagadzirwa nemvura, uye mushonga unobaiwa unoshandiswa kamwe chete zvinhu zvakasiyana. Mazuva azvo anoenderana nezvinhu zvacho, musanganiswa wazvo, kurongedzwa, mamiriro ekuchengetwa, uye humbowo hunotsigira kusachinja kwemhando yazvo.
Tanga nemudziyo wako pachako. Tsvaga nhamba yeboka rayakagadzirwa naro, mirayiridzo yekuchengetwa, uye zuva rekupera nguva kana zuva rayakanakisisa kushandiswa risati rasvika. Wozotarisa kana paine mumwe murayiridzo une chekuita nekuvhura kana kugadzira. Mashoko ari paindaneti akadai sekuti “methylene blue inogara kwemakore” haagoni kuratidza kuti bhodhoro iroro rinoramba rakakodzera kushandiswa kwenguva yakareba sei.
Zvinonyatsotsanangurwa nezuva racho
Pamishonga, FDA inotsanangura kuti mazuva ekupera nguva anoratidza kusachinja kwemhando kwakaratidzwa pasi pemamiriro ekuchengetwa akanyorwa pachigadzirwa. Kusachinja kwemhando kunosanganisira kuramba paine simba, mhando, uye kuchena zvinodiwa. Zuva racho rinoenderana nehumbowo hwechigadzirwa, kwete nezita rechinhu chikuru chiri machiri chete.
Mazuva akasiyana anopindura mibvunzo yakasiyana:
- Zuva rekugadzirwa kana kubvumidzwa kuburitswa: pakaitika danho rekugadzira kana chisarudzo chekubvumidza boka rezvigadzirwa kuti riburitswe. Izvi hazvirevi zvoga kuti ndiro zuva rekupedzisira rekushandisa.
- Zuva rekupera nguva kana rekupedzisira rekushandisa: magumo enguva yakatarwa yechigadzirwa ichocho pasi pemamiriro acho akataurwa.
- Zuva rekuongororwazve: nguva apo chinhu chinoda kuongororwazve zvakakodzera zvichienzaniswa nezvinodiwa zvacho. Haisi mvumo yekuwedzera nguva yekushandisa nekungotarisa ruvara.
- Muganhu wepashure pekuvhura kana kugadzira: mirayiridzo inoshanda kana kurongedzwa kwekutanga kwavhurwa kana musanganiswa wachinjwa. Pamushonga wakagadzirwa ukapiwa nemukhemisi, izvi zvinogona kuratidzwa pazvakanyorwa nemukhemisi sezuva risingafaniri kupfuudzwa pakushandisa.
Gwaro reMerck rinotaura nezvemazuva ezvigadzirwa rinosiyanisa mazuva ekuburitswa, ekupera nguva, uye ekuongororwazve. Musiyano uyu unokosha paunoverenga chitupa chechinhu chinoshandiswa kugadzira chigadzirwa. Zuva rekuongororwazve rehupfu hwemethylene blue hariratidzi zuva rekupera nguva rechinonyungudutswa chinozogadzirwa nehupfu ihwohwo. Uyewo, zuva rechigadzirwa chisati chavhurwa haringopinduri mibvunzo yose pamusoro pemudziyo wakavhurwa.
Methylene blue inoda kuiswa mufiriji here?
Usangoiisa mufiriji pasina murayiridzo. Tevedzera murayiridzo wetembiricha wechigadzirwa chaicho.
Mirayiridzo yeBlupreme yekuchengetwa kwechinonyungudutswa inoti bhodhoro richengetwe rakamira, ridzivirirwe pachiedza, uye tembiricha ive pasi pe25 °C. Inoti kuisa mufiriji hakudiwi uye chinonyungudutswa hachifaniri kuomeswa nechando. Chengeta bhodhoro rakanyatsovharwa uye tevedzera zuva rayakanakisisa kushandiswa risati rasvika rakanyorwa pakurongedzwa kwacho. Mibvunzo inowanzobvunzwa haisati yataura nguva yakasiyana yepashure pekuvhura; kusataurwa kwayo hakupi humbowo hwenhamba yemwedzi inongofungidzirwa.
Chimwe chigadzirwa chinopa muenzaniso unobatsira pakuenzanisa. Chinyorwa chemushonga unobaiwa wePROVAYBLUE chinotaura 20–25 °C, kuchibvumira kutsauka kwetembiricha kusvika pa15–30 °C. Chinorambidza pachena kuisa mufiriji nekuomesa nechando, chinoda kurongedzwa kwekutanga kuti chidzivirire pachiedza, uye chinorayira kuraswa kwezvasara zvisina kushandiswa mumidziyo yacho yekushandisa kamwe chete. Mirayiridzo iyi ndeyemushonga iwoyo. Haisi mirayiridzo yekuchengetwa kana kushandiswazve kwebhodhoro rinotengeswa rine mudziyo wekudonhedza.
Saka pfungwa yekuti “kana kuchitonhora zvakanyanya zvinotova nani” haisi mutemo wakavimbika. Kana chigadzirwa chikaoma nechando pakutakurwa kana bhodhoro rikapedza maawa mumotokari inopisa, nyora zvakaitika uye bvunza mugadziri kana chigadzirwa chichiri chakakodzera. Kuchidzorera patembiricha inokurudzirwa hakuratidzi kuti zvakaitika hazvina kuchikanganisa.
Hupfu hunoda mirayiridzo yahwo
Kuchengetwa kwehupfu hakusi kungochengeta chinonyungudutswa chabviswa mvura. Verenga zvakanyorwa pakurongedzwa uye gwaro reruzivo rwekuchengeteka rwechinhu chakapiwa. Mirayiridzo yechigadzirwa chehupfu cheBlupreme inoti kurongedzwa kunofanira kunyatsovharwa, mamiriro ave akaoma, uye chigadzirwa chidzivirirwe pachiedza.
Semumwe muenzaniso wakanangana nechigadzirwa, mirayiridzo yeMerck yeCertistain methylene blue inotaura 5–30 °C pachinhu ichocho chakaoma chinoshandiswa pakushanda nemaikorosikopu. Inobvumira zviri mumudziyo kushandiswa kusvika pazuva rakataurwa rekupera nguva pashure pekuvhurwa kwekutanga kana mamiriro iwayo akachengetedzwa uye bhodhoro richiramba rakanyatsovharwa. Izvi hazvipi zuva rimwe chete kuchinonyungudutswa chinogadzirwa nehupfu ihwohwo chekupa ruvara murabhoritari.
Usati watenga paki hombe, tarisa kana uchigona kuishandisa mukati menguva yakanyorwa mumagwaro ayo uye kuiramba yakavharwa pakati pekushandisa. Gwaro rekutenga hupfu rinotaura nezvedanho remhando, ukuru hwepaki, uye mibvunzo ine chekuita nemagwaro.
Runyorwa rwekuongorora kuchengetwa ruchibva pachinyorwa chechigadzirwa
Shandisa tafura iyi mudziyo negwaro reboka rezvigadzirwa rinoenderana nawo zviri pamberi pako. Nyora mirayiridzo chaiyo muchikamu chekupedzisira. Nzvimbo isina kunyorwa inoratidza mubvunzo unofanira kupindurwa, kwete mamiriro aunofanira kufungidzira.
| Chekuongorora | Chinonyungudutswa chakagadzirwa | Hupfu hwakapiwa | Zvinonyorwa zvechigadzirwa ichi |
|---|---|---|---|
| Kuzivikanwa | Chigadzirwa chaicho, kusimba kwemusanganiswa, kushandiswa kwakatarwa | Chigadzirwa chaicho, danho remhando, chimiro chachakapiwa chiri | Chigadzirwa: ______ |
| Boka rekugadzirwa | Enzanisa bhodhoro nemagwaro | Enzanisa paki nechitupa | Boka: ______ |
| Rudzi rwezuva | Kupera nguva/zuva rayakanakisisa kushandiswa risati rasvika uye chero zuva rekupiwa nemukhemisi | Kupera nguva kana kuongororwazve, kwete zuva rekuburitswa chete | Rudzi/zuva: ______ |
| Tembiricha | Nyora muganhu wetembiricha nemurayiridzo wekuomesa nechando/kuisa mufiriji | Nyora muganhu wetembiricha wakanangana nehupfu | Mamiriro: ______ |
| Chiedza nehunyoro | Nyora zvinodiwa pakudzivirira pachiedza | Nyora zvinodiwa pakudzivirira pachiedza nekuchengetera pakaoma | Nzvimbo: ______ |
| Kuvharwa | Bhodhoro rekutanga, chivharo, uye chero bhokisi rinodiwa | Paki yekutanga uye kuvharwazve kwakakwana | Kuvharwa kwaongororwa: ______ |
| Pashure pekuvhura | Nyora zuva rekuvhura uye muganhu wakataurwa wenguva yekushandisa | Tarisa kana kuvhura kuchichinja nguva yakataurwa | Yakavhurwa/muganhu: ______ |
| Yakaderedzwa kusimba kana kugadzirwa | Wana mirayiridzo yemusanganiswa wachinjwa | Usashandise mazuva ehupfu pachinonyungudutswa chitsva | Gwaro rinoshanda: ______ |
| Chiitiko pakuchengetwa | Nyora nezvekupisa, kuoma nechando, kubuda mumudziyo, kana kufungira kusvibiswa | Nyora nezvehunyoro, kurongedzwa kwakakuvadzwa, kana kutsauka pamamiriro ekuchengetwa | Chiitiko/danho: ______ |
Nei mudziyo nekudzivirirwa pachiedza zvichikosha
Chengeta chinyorwa chekutanga nekurongedzwa kwekutanga kunze kwekunge mirayiridzo yechigadzirwa ichiti uite zvimwe. Bhodhoro rinotsiva rekutanga rinogona kusiyana pakudzivirira pachiedza, pakuvharwa, uye pakukodzera kwezvinhu zvarakagadzirwa nazvo kuchigadzirwa. Tsananguro yeFDA yekuedza kusachinja kwemhando inoratidza misiyano yemusanganiswa neyemudziyo nemavharirwo awo sezvinhu zvinokanganisa kutarwa kwemazuva echigadzirwa.
Bhodhoro reruvara rwebrown rwakaita serweamber hariiti kuti chiedza chezuva chakananga chive chinogamuchirika. Isa chigadzirwa munzvimbo inoenderana nemirayiridzo yacho uye inodzivisa kupisa kunogona kutarisirwa. Pabhodhoro rakavhurwa rine mudziyo wekudonhedza, usagunzva mudziyo wekudonhedza nemaoko, muromo, kana nzvimbo dzekushandira; rivhare nokukurumidza. Usafungidzira kuti ruvara rwedhayi runoratidza kuti chigadzirwa chakakodzera panyaya yeutachiona. Tsananguro yehunyanzvi pamusoro pechiedza, pH, zvinhu zvinonyungudutsa, uye kusachinja kwemethylene blue inotsanangura kuti nei zviedzo nemisanganiswa zvichida mamiriro azvo pachazvo.
Mazuva asipo kana kutaridzika kwachinja
Kana usingakwanisi kuwana zuva, kumbira mutengesi kuti aratidze gwaro reboka rezvigadzirwa rinoshanda uye atsanangure kana chigadzirwa chine zuva rekupera nguva, zuva rekuongororwazve, kana mumwe muganhu wekushandisa wakanyorwa. Bvunza zvakasiyana nezvekushandisa pashure pekuvhura. Tsananguro yeSigma-Aldrich yekutsigira zvigadzirwa inotaura pachena kuti kusavapo kwezuva rekupera nguva kana rekuongororwazve kunogona kuratidza kusakwana kweruzivo rwakakodzera rwekusachinja kwemhando kuti nguva yekugara kwechigadzirwa itarwe. Kushayikwa kweruzivo hakusi humbowo hwekuti mhando inoramba isingachinji nokusingaperi.
Kuva nemakore mukati zvisingatarisirwi, zvimedu, kubuda mumudziyo, kana chisimbiso chakakuvadzwa zvinoda kuti urege kushandisa uye utevedzere mirayiridzo yechigadzirwa. Bhodhoro rinotaridzika sezvarinofanira harirevi kuti rapasa bvunzo yekupera nguva. Ukuwo, kusviba kwega kunogona kuratidza kutorwa kwakanyanya kwechiedza nechinonyungudutswa chine kusimba kukuru. Verenga nezvezvinonyungudutswa zvakasvibira, zvine makore mukati, kana zvinenge zvitema uye zvinhu zvinobuda mumusanganiswa zvichidzika pasi nemakristaro usati wati kuchinja kwekutarisika kunokonzerwa nechinhu chimwe chete. Usapisa, kusefa, kana kusanganisazve chigadzirwa chausina chokwadi nacho kuti chitaridzike sechakakodzera zvakare.