Chinyorwa
Methylene blue mukurapa mazino: kushandisa dhayi netsvakurudzo yephotodynamic
Methylene blue ine mabasa akasiyana mukurapa mazino nemutsvakurudzo. Inogona kuita kuti panofungidzirwa kutsemuka kwezino panyatsooneka apo chiremba wemazino anenge achiongorora. Mukurapa kwephotodynamic kunorwisa utachiona, inoshanda sechinhu chinokurudzirwa nechiedza, ichishandiswa pamwe nechiedza chinodzorwa. Vatsvakurudzi vemurabhoritari vanodzidzawo zvainoita kumasero emazino. Kushandiswa uku kunopindura mibvunzo yakasiyana uye hakugoni kupa humbowo hunosimbisa kumwe kushandiswa.
Musiyano iwoyo unokosha kana kutsvaga “kushandiswa kwemethylene blue pamazino” kuchibva pamufananidzo wakatorwa nemakorosikopu kuchienda pakurudziro yechizoro chemazino. Mutsetse webhuruu unooneka chinhu chacherechedzwa. Kuderera kwemabhakitiriya mumasampuli chinhu chakabuda mukurapa. Hapana chimwe chezviviri izvi chinoratidza kuti kukwesha mazino nedhayi kunodzivirira maburi kana kuponesa zino rakakuvara.
Batanidza kushandiswa kwacho nemamiriro acho
Tafura iyi yekushandiswa inopatsanura chinhu chinoshandiswa, mubvunzo uri kubvunzwa, uye mhedziso inogona kutsigirwa nehumbowo. Misanganiswa yakashandiswa muzvidzidzo inotaurwa kuti izivikanwe, kwete semirayiridzo yekuigadzira.
| Kushandiswa | Musanganiswa nemamiriro ekushandiswa | Zvazvinogona kuratidza | Zvazvisingaratidzi |
|---|---|---|---|
| Kuona panofungidzirwa kutsemuka | Mushonga wedhayi wakasarudzwa nachiremba; kuongorora mazino uchikudza zvinoonekwa | Kuwedzera kuoneka kwemutsara kana chimwe chinhu chiri panosvikika | Kudzika kwese kwekutsemuka, mamiriro enyama iri mukati mezino, kana kuti kubvisa zino kunodiwa here |
| Kurapa kwephotodynamic mugero wemudzi wezino | Chinhu chinokurudzirwa nechiedza chakanangana nechidzidzo uye kuendesa chiedza mukati meg ero rinorapwa nenyanzvi | Shanduko muutachiona hwakatorwa mumasampuli kana zvimwe zvabuda zvakafanotemerwa | Kubviswa kweutachiona hwese kana kuramba kwezino riripo kwenguva refu zvichingobva pakuverengwa kwemabhakitiriya |
| Kurapa kwephotodynamic matishu akapoteredza mazino | Mushonga wedhayi unoshandiswa panzvimbo yacho pamwe nechiedza chakatarwa, kazhinji zvichidzidzwa pamwe nekurapa kunoitwa nemidziyo | Zvimwe zvazvinowedzera zvichienzaniswa neboka rakakodzera rokuenzanisa naro | Chinotsiva kubviswa kwerukoko rwetsvina ine mabhakitiriya nedombo remazino |
| Tsvakurudzo yemasero emazino | Musanganiswa wakatarwa wokurera masero uye zvinhu zvaanoiswa pazviri murabhoritari | Maitiro emasero mumamiriro iwayo emuedzo | Kubatsira kunobva pakuisa dhayi pamazino emurwere |
| Chizoro chemazino chemethylene blue chinogadzirwa kumba | Musanganiswa usina mwero wakatarwa uye kuiswa kwawo mumuromo kakawanda | Hapana mhedziso pamusoro pekushanda kwacho inogona kubva pakushandiswa kwataurwa pamusoro | Kudzivirira maburi kwakatsigirwa nehumbowo, kurapa chirwere chenyama yakapoteredza mazino, kana chirongwa chakachengeteka chekushandisa kumba |
Methylene blue inogona kuratidza zino rakatsemuka here?
Inogona kubatsira chiremba kuona mutsetse unofungidzirwa. American Association of Endodontists inotsanangura kushandisa dhayi remethylene blue pamwe nekukudza zvinoonekwa, kupfuudza chiedza muzino, kuedza kuruma, uye kuongorora matishu akapoteredza zino nemudziyo wekuyera pakuongorora zino rakatsemuka. Kushandisa dhayi chimwe chete chezvikamu zvekuongorora ikoko. Chinyorwa ichocho chenyanzvi chinosimbisa kukosha kwekuongorora kuti kutsemuka kunosvika papi uye chinoti hapana kuongorora kwakajairika kunogona kufanotaura mhedzisiro yenguva refu kuri kwega.
Makorosikopu inokudza chikamu chinogona kuonekwa; haiiti kuti nzvimbo dzese dzakavanzika dzioneke. Naizvozvo mutsetse une dhayi unofanira kududzirwa zvichienderana nemaumbirwo ezino nezvimwe zvawanikwa. Haukwanisi uri woga kuratidza kana nyama iri mukati mezino iine utano, kuziva zvese zviri kukonzera marwadzo, kana kusimbisa kuti zino harichagoni kugadziriswa.
Musiyano uripo pakati pemhando dzekutsemuka unokoshawo. Gwaro reAAE rinotsanangurira varwere nezvemazino akatsemuka rinopatsanura mitsara isina kudzika iri pagoko rezino kubva pamapundu epamusoro pezino akatyoka, mazino akatsemuka, mazino akaparadzana, uye kutsemuka kunotevedza kureba kwemudzi wezino. Kurapa kunoenderana nemhando, nzvimbo, uye kukura kwekutsemuka. Kuwana mutsetse hakuna kufanana nekuwana zino rakaparadzana.
Kana chiremba wemazino akaronga kubvisa zino mushure mekushandisa dhayi, mibvunzo inobatsira ndeiyi: “Rakatsemuka nerudzii?”, “Ndezvipi zvawanikwa zvinoratidza kuti kutsemuka kwacho kunosvika papi?”, uye “Zvawanikwa izvozvo zvinobatsira sei kusarudza kana zino richigona kugadziriswa?” Mibvunzo iyi inokumbira tsananguro yezvikonzero zviri shure kwerudziro yacho. Mutsetse wakasviba zvikuru uri woga hausi tsananguro iyoyo.
Nei kumwe kuongorora mazino kuchiri kukosha
Murwere anogona kubvunza zvine musoro kuti nei kumwe kuongorora kuchidiwa mushure mekutorwa mufananidzo nesikani kana kuongororwa nemakorosikopu. Miedzo yakasiyana inoongorora zvikamu zvakasiyana zvedambudziko. Hurongwa hweAAE hwekuongorora mazino akatsemuka neakatyoka hunosanganisira kuongorora nyama iri mukati mezino, zvakawanikwa pamatishu akapoteredza zino, kuona zino, uye kutora mifananidzo kuitira kuti chiremba azive mamiriro enyama iri mukati mezino uye enzvimbo iri kumucheto kwemudzi.
Somuenzaniso, muedzo unoshandisa kutonhora kana magetsi unoongorora kudavidza kwenyama iri mukati mezino. Kuongorora nemudziyo wekuyera kunoongorora matishu akapoteredza zino. Kupfuudza chiedza muzino kunoongorora mafambiro echiedza. Dhayi rinoita kuti zviri pamusoro pezino zvinyatsooneka. Zvinocherechedzwa izvi zvinogona kutsigira tsananguro imwe chete, kana kusiya kusava nechokwadi kunoda kumwe kuongorora. Kudzokorora muedzo mumwe unopa zvinonyatsooneka hakungotsivi mimwe miedzo.
Kurapa kwephotodynamic kunoshandisa dhayi neimwe nzira
Muk urapa kwephotodynamic kunorwisa utachiona, kunowanzopfupikiswa kuti aPDT, methylene blue inotora chiedza chakakodzera uye inobatanidzwa mukuita kwemakemikari kunokonzerwa nechiedza kunogona kukuvadza utachiona. Izvi zvinoda musanganiswa wakatarwa wechinhu chinokurudzirwa nechiedza uye kushandisa chiedza chinodzorwa. Hukama huri pakati pemethylene blue nechiedza chitsvuku hunotsanangura nei kureba kwemafungu echiedza, nzira yokuendesa chiedza, uye kuiswa pachiedza zviri zvikamu zvekurapa kwacho.
Naizvozvo kurapa kuri kuongororwa mubatanidzwa wezvinhu, kwete “methylene blue” chete. Muedzo wekurapa matishu akapoteredza mazino wakagovera vanhu 36 mumapoka zvisina kusarudza wakaenzanisa methylene blue iri mumvura nem usanganiswa une chinhu chinoderedza kukakavadzana kwepamusoro pemvura, uchishandisa chiedza che660-nm mushure mekubvisa dombo remazino nekutsvedzerera pamusoro pemidzi. Chidzidzo chacho chakataura kuti pakanga pasina musiyano wakakosha pakati pemapoka mukuderedzwa kwemabhakitiriya kana muchiyero chekurapa chakanga chaongororwa. Kuchinja chinhu chakanga chakasanganiswa nedhayi hakuna kungounza imwe betsero inobatsira pakurapa.
Miedzo yekurapa mazino inoratidzei?
Zvinobuda zvinoenderana nedambudziko riri kurapwa, nzira yakatarwa, chinhu chiri kuenzaniswa nacho, uye chinoyerwa. Zvidzidzo zviviri zvekurapa migero yemidzi yemazino zvinoratidza nei chirevo chakadai sekuti “inouraya mabhakitiriya emazino” chakafara zvakanyanya kuti chitungamirire kurapa.
Mune muedzo wa2020 wakagovera mazino epamberi emukaka 30 aiva nenyama yemukati yakafa mumapoka zvisina kusarudza, kuwanda kwemabhakitiriya kwakaderera ne93% pakurapa kwakajairika uye ne99% pakurapa kwakajairika pamwe neaPDT. Musiyano wacho wakanga usina kukosha pakuongorora kwenhamba. Chikamu chikuru ichocho hachina kuratidza kuti imwe nzira yakawedzerwa yaiva nani mumuedzo iwoyo.
Muedzo wekurapa wa2023 waisanganisira migero yemidzi yemazino 24 wakawana kuderera kwakanyanya, kwakakosha pakuongorora kwenhamba, mumabhakitiriya aipenyu uye muzvikamu zviviri zvinobva mumabhakitiriya apo aPDT yakatevera kugadzirira kwakajairika. Izvozvo zvinotsigira zvakawanikwa pakuderedza utachiona zvakanangana nenzira iyoyo yakatarwa. Hazviratidzi, zviri zvoga, kuti mazino mashoma anozobviswa kana kuti mazino anoramba aripo zviri nani kwenguva refu.
Nhungamiro dzinotarisawo humbowo hwakakura hunobva muzvidzidzo zvakawanda. Nhungamiro yeEuropean Federation of Periodontology yedanho rechipiri rekurapa periodontitis yezvikamu I–III, yakavakirwa panhungamiro yayo yeS3 ya2020, inopa zano rekusawedzera kurapa kwephotodynamic pamafungu echiedza akatarwa e660–670-nm kana 800–900-nm pakuchenesa nemidziyo pasi penyama yakapoteredza mazino. Kurudziro iyi ine chekuita nekurapa matishu akapoteredza mazino; haifaniri kungoiswa pane zvese zvinogona kurapwa pamazino.
Zvinowanikwa pamasero emazino hazvisi humbowo hwechizoro chemazino
Chinyorwa chinowanzova nechokuita nenyaya iyi chinotaura nzira yekushanda yakasiyana zvachose. Muchidzidzo chemurabhoritari chaMikulás nevamwe cha2020, vatsvakurudzi vakaisa masero ekutanga anogona kushanduka kuva mamwe masero, akatorwa munyama iri mukati memazino evanhu, uye mitochondria dzakaparadzaniswa kubva muuropi pachinhu chimwe chete chinovaka resini, chinonzi TEGDMA. Methylene blue yakadzorera zvishoma zvimwe zviyero zvekushanda kwemitochondria zvakanga zvakanganisika mumamiriro iwayo emuedzo.
Basa iri rakaongorora kugadzirwa nekushandiswa kwesimba mumasero. Harina kuyedza vanhu vachikwesha mazino, kudzivirira maburi, kuporesa kutsemuka kwezino, kana chizoro chemazino chakagadzirwa chakakwana. Masero evanhu ari murabhoritari anoramba achingopa humbowo hwemurabhoritari. Musiyano unotsanangurwa mudura retsvakurudzo pakati pemiedzo pavanhu nezvidzidzo zvekuyedza murabhoritari unobatsira kududzira rudzi urwu rwezvinobuda.
Zvinorevei izvi kune zvinotaurwa pamusoro pechizoro chemazino nekuchengetwa kwemuromo?
Humbowo huri pamusoro hahusimbisi chirongwa chekushandisa methylene blue pamazino kumba. Kuwedzera dhayi muchizoro chemazino kunochinja musanganiswa wakagadzirwa wakakwana pasina kuratidza kuti musanganiswa mutsva unoshanda zvinobatsira, kuti kuushandisa kakawanda kunogamuchirika, kana kuti unoenderana nezvinhu zvakashandiswa kugadzirisa mazino. Chiedza chinoshandiswa nevatengi hachibudisiwo nzira yakatarwa yephotodynamic inoitwa nenyanzvi.
Kana pakarongwa nzira yekurapa mazino, bvunza kuti inogadzirisa dambudziko ripi rakaonekwa, inowedzera betsero ipi pakurapa kwakajairika, uye ndechipi chidzidzo chakayedza betsero iyoyo. Kana pachitaurwa zvinonzi zvinoitwa nechizoro chemazino, kumbira humbowo pamusoro pechigadzirwa chacho chakagadzirwa chakakwana uye chinonzi chinoitwa nacho. Chinyorwa pamusoro pekuderedza utachiona mumigero yemidzi yemazino hachigoni kuzadza mukaha iwoyo. Saizvozvowo, miedzo yephotodynamic yekurapa lichen planus yemumuromo uye humbowo pamusoro pezvironda zvemumuromo nekurwadza kwehuro zvine chekuita nematambudziko akasiyana anoda kuongororwa kwawo oga.