Tuhinga
Ngā painga o te puru metilīni: he aha e tautokona ana e te rangahau tangata
He whakamahinga hauora tō te puru metilīni kua whakaaturia, engari kāore tēnā e whakapūmau ana i tōna tika hei tāpiringa hauora whānui. Kei roto i te rangahau tangata ngā whakamātautau iti mō te mahara me te pākia o te roro, ngā rangahau ki ētahi rōpū tūroro motuhake, me ngā putanga kāore e hāngai ana ki ngā kerēme rongonui mō te whakapiki pūngao. Ko te pātai whaihua: he painga mō wai, ā, mā tēhea putanga e ine?
Ka taea e tētahi rongoā te whakatika i tētahi tukanga mate motuhake, engari kāore e whakapai ake i tētahi pūnaha kua hauora kē. Ka whakaatu pea tētahi rerekētanga i te matawai roro kei te mahi tētahi matū, engari kāore e whakaatu ana kua mārama ake te whakaaro o te tangata. Mā te pupuri i aua wehewehenga ka rerekē te whakamāramatanga o ngā taunakitanga.
Ko tēhea painga kua whakapūmautia?
I te United States, e tautuhi ana ngā mōhiohio whakahau rongoā mō ProvayBlue ka tukuna ki roto i te ia toto i te maimoatanga o te methemoglobinemia kua hua ā-muri i ngā pakeke me ngā tamariki. I tēnei mate, ka hurihia te hemoglobin e te whakahāora, kia kore ai e kawe noa i te hāora. Ka āwhina te puru metilīni ki te whakahoki i taua hemoglobin kua hurihia ki tōna āhua mahi.
He maimoatanga motuhake tēnei, he whakaritenga matū, he ara tuku, he tātaritanga mate, he aroturuki hoki kua tautuhia. Ehara tēnei i te tohu ka whakapiki tētahi wairewa ā-waha e hokona ana i te toa i te tukunga hāora, ka whakapai rānei i te hauora o tētahi kāore ōna methemoglobinemia. Ko te wehewehenga e pā ana ki tā te rangahau i whakaatu ai, ehara i te pātai mēnā he mahi koiora tō te matū.
Ripanga taunakitanga mō ia kerēme
Ka wehe tēnei ripanga i ngā putanga mō ngā tūroro i ngā inenga whakamātautau. He mahere taunakitanga e aro ana ki ētahi take, ehara i te rārangi o ngā whakamahinga katoa kua whakaarohia. Ko tētahi kitenga pai e hāngai ana ki ngā āhuatanga rangahau e whakaaturia ana.
| Kerēme painga | Rōpū tangata me ngā āhuatanga rangahau | Putanga i inea me te kitenga | Herenga matua |
|---|---|---|---|
| Te maimoa i te methemoglobinemia kua hua ā-muri | Ngā pakeke me ngā tamariki e whiwhi ana i tētahi hua whakahau rongoā ka tukuna ki roto i te ia toto | Ko te whakahokinga o te hemoglobin mahi te pūtake o te whakamahinga kua whakaaetia i runga ake nei | He maimoatanga mō tētahi mate motuhake, ehara i te taunakitanga mō te whakapiki oranga whānui |
| Te whakapai ake i te mahara, i te aro rānei | Whakamātautau matapōkere o 2016: 26 pakeke hauora; kotahi tukunga mā te waha, ka whakatauritea ki te matū horihori; ka whakamātauria kotahi hāora i muri mai | I rerekē te mahi roro e pā ana ki te mahi whakamātautau; tata ki te 7% te whakapaitanga o ngā whakautu tika mō te tiki mahara i roto i te rōpū puru metilīni | Kāore te whakataurite pāhekoheko rongoā-me-te-wā mō te whanonga i whai hiranga tauanga, P = .09; kāore te wā urupare i te whakamātautau aro i pai ake |
| Te whakapiki pūngao o te roro | Whakamātautau whakawhiti o 2023: tokowaru wāhine hauora; puru metilīni ki roto i te ia toto i ngā taumata pānga e rua, me te matū horihori i ngā rā rerekē | I heke te rere toto o te roro me te pākia hāora i whakatau tatahia | He rangahau iti mō ngā pānga wā-poto ki ngā mahi ā-tinana; ehara i te whakamātautau oranga mā te tukunga ā-waha, ehara hoki i te tohu mō te kino, mō te painga haumanu rānei |
| Te whakapai ake i te mate pōuri, i te manawapā rānei | Te whakamātautau mate bipolar a Alda me ōna hoa: 37 kaiuru e tango ana i te lamotrigine; he whakamātautau whakawhiti e ono marama, e whakataurite ana i ngā rahinga ā-waha teitei ake me ngā rahinga iti ake | I pai ake ngā tohu mate pōuri me te manawapā e toe ana; kāore ngā pānga ki te hinengaro i whai hiranga tauanga | He maimoatanga tāpiri i tētahi rōpū tūroro kua tīpakohia; he rongoā hohe iti ake te rahinga hei whakataurite; kāore e taea te whakapūmau i te whakapaitanga whānui o te wairua |
| Te maimoa i te mate Alzheimer | Whakamātautau LMTM wāhanga 3 o 2016: 891 tūroro he māmā, he āhua taumaha rānei te mate; 15 marama | Kāore ngā tātaritanga matua kua whakaritea i mua i kite i tētahi painga ki te hinengaro, ki ngā mahi o ia rā rānei, mō ngā rahinga teitei ake ina whakatauritea ki te rōpū whakahaere rahinga iti | He whakaritenga motuhake a LMTM o te methylthioninium kua whakahekea ā-matū; kāore ōna putanga e whakamana i ngā pata puru metilīni e hokona ana i te toa |
| Te whakapai ake i te whakaoranga mai i te ohorere nā te sepsis | Whakamātautau o 2023 i tētahi pokapū kotahi: 91 tūroro i tātaritia; he maimoatanga ki roto i te ia toto i tāpirihia ki te tiaki whāomoomo, ka whakatauritea ki te matū horihori | Ko te tau waenga o te wā kia whakamutua ngā rongoā whakakapi ia toto he 69 hāora, ka whakatauritea ki te 94 hāora | He rite te auau mate; kāore i rawaka te kaha tauanga o te whakamātautau hei whakapūmau i tētahi painga mō te ora tonu; he horopaki maimoatanga hōhipera |
| Te whakaroa i te kaumātuatanga o te kiri | Ngā whakamātautau fibroblast me te kiri hanga anō o 2017: ngā pūtau tangata kua whakatipuria me ngā tauira kiko ahu-toru | I roto i ngā rerekētanga ko te hekenga o te ahotea whakahāora me te pikinga o te makuku me te mātotoru o te kiri tauira | Ehara te rawa nō te tangata i te whakamātautau ki ngā tāngata; kāore he taunakitanga i konei e mea ana ka whakaiti te inu puru metilīni i ngā korukoru |
| Te whakaroa i te roanga ora o te tangata | E matapaki ana te arotake whakaroa kaumātuatanga o 2021 i ngā tukanga mahi, ngā whakamātautau pūtau, ngā rangahau kararehe, me ētahi rangahau haumanu kua tīpakohia | He take koiora e taea ai te whakapono, me ngā pānga whakamātautau e pā ana ki te kaumātuatanga | Ehara te arotake i te whakamātautau roanga ora tangata; kāore ngā kitenga kua tohutohua e whakapūmau ana i te roa ake o te ora o te tangata |
He pēhea te nui o tā te rangahau mahara e whakaatu ana?
Me hono te tau 7% ki tōna whakataurite. Ko te whakapaitanga mai i te taumata tīmatanga o tētahi rōpū ehara i te mea kotahi ki tētahi painga kua whakaaturia ki runga ake i te matū horihori. Mā te tāruarua i tētahi mahi ka pai ake pea te whakatutuki nā te taunga ki taua mahi; koirā tētahi take e whai tikanga ai te rōpū whakahaere.
I te whakamātautau i runga ake nei, kāore te whakataurite tauanga o ngā rerekētanga o ngā rōpū i eke ki te paepae hiranga e whakamahia whānuitia ana. Kāore tēnā e whakamātau ana kāore he pānga. Engari e tohu ana he kitenga tōmua noa te kitenga whanonga. Kāore hoki te pikinga o te mahi roro e pā ana ki te mahi whakamātautau, e kitea ana i ngā whakaahua, e whakapūmau ana kua pai ake te aro o ia rā, te whakatutuki mahi, te ārai rānei i te mate wareware. Tirohia te arotake taunakitanga mō te mahara me te hinengaro mō te aromatawai e hāngai ana ki ia putanga.
Ka whakapiki te puru metilīni i te pūngao?
Ko te tikanga o te “pūngao” pea ko te iti ake o te ngenge, te whakaputa ATP nui ake i ngā pūtau, te whakamahi hāora nui ake, te kori tinana roa ake rānei. He putanga rerekē ēnei hei ine. Kāore e tika kia whakakapia noatia ngā taunakitanga mō tētahi ki ngā taunakitanga mō tētahi atu.
He tino whai mōhiohio te rangahau ki ngā wāhine tokowaru, nā te mea i matapae ngā kairangahau ka piki te pākia o te roro, engari ko te ritenga kē tā rātou i kite ai. I kitea hoki i ētahi whakamātautau kiore motuhake te hekenga o te rere toto me te pākia kūhuka i raro i ngā āhuatanga i whakamātauria. I matapaki ngā kaituhi i ngā pānga e whakawhirinaki ana ki te rahinga, me te tūponotanga ka rerekē te urupare a ngā roro hauora i tērā o ngā pūnaha kua ngoikore.
Kāore tēnei e tautuhi ana i tētahi taumata pānga kē e whakapiki pono ana i te pūngao. He rerekē hoki ngā āhua pānga ka hua mai i te tukunga ki roto i te ia toto me te tukunga mā te waha. E tautoko ana te rangahau i te whakamātautau tika i tētahi tukanga mahi, kaua i te whakapae ka piki tonu te mahi a ngā mitokōria. Ka āta tirohia taua wehewehenga i tā mātou arotake taunakitanga mō ngā mitokōria.
He aha ngā kitenga kararehe me ngā kitenga pūtau e kore ai e whakatau i ngā kerēme hauora?
Ka āwhina ngā whakamātautau i mua i te rangahau haumanu ki te tautuhi i ngā tukanga mahi, me te whakatau he aha e tika ana kia whakamātauria ki te tangata. Ka taea te whakahaere tino tika i te kukū o te matū huri noa i tētahi pūtau, te whakaputa i tētahi wharanga motuhake ki tētahi kararehe, te ine rānei i ngā rerekētanga kiko kāore e ngāwari te rangahau ki te tangata.
Ko aua painga anō e whakawhāiti ana i te whakamahinga o ngā kitenga ki te tangata. Ko te tiaki i tētahi pūtau kua whakapēhia i roto i te whakamātautau kāore e whakaatu ana ka pai ake te āhua o tētahi pakeke hauora. Kāore tētahi tauira kiri hanga anō e tārua ana i te rere toto o te tangata, tōna pākia, tōna whakamahi rongoā, me ngā tau o te pānga ki a ia. He tauira mārama te rangahau kiri: ahakoa nō te tangata te kiko, kāore e huri ngā inenga kiko taiwhanga hei putanga haumanu mō te āhua o te kiri.
Waihoki, ka taea e tētahi arotake kei roto i tōna taitara te “whakaroa kaumātuatanga” te whakarāpopoto i ngā whakamātautau whai tūmanako, me te kore e whakapūmau i te ora roa ake. Wehea te putanga e whakaarohia ana i te putanga i tino inea. Ka whai te arotake taunakitanga mō te ora roa me te whakaroa kaumātuatanga i taua pātai puta noa i te rangahau.
He rerekē ngā painga mō ngā tāne me ngā wāhine?
Kāore ngā rangahau e wātea ana e whakapūmau i ngā painga oranga whānui motuhake mō ia ira tangata. Mā tētahi tauira rangahau mahi ā-tinana he wāhine katoa ōna kaiuru ka mōhio tātou ko wai i whai wāhi; ki te kore he whakataurite ki ngā tāne, kāore e taea te whakaatu he urupare motuhake tō ngā wāhine. Me whai tau kaiuru rawaka hoki ngā rangahau e whakauru ana i ngā ira e rua, me tētahi whakataurite kua whakamaheretia, i mua i te tautoko i ngā kerēme mō ngā pānga rerekē.
Mō ngā tāne, kāore te rangahau i tirohia i konei e whakapūmau i ngā painga mō te testosterone, te āhei whakaputa uri, te kaha ai rānei. Mō ngā wāhine, kāore e whakapūmau i te whakamāmātanga o ngā tohu ruahinetanga, i te whakataurite taiaki rānei. Kāore ngā rapunga hāngai mō ngā whakamātautau testosterone me te ruahinetanga i kitea he taunakitanga maimoatanga tangata e whakaponohia ana mō aua kerēme. He kōrero tēnā mō ngā taunakitanga i kitea, ehara i te tohu kua whakakorea ngā pānga katoa e taea ana.
Ka rerekē te aromatawai tūraru i te hapūtanga: e whakatūpato ana te tapanga rongoā whakahau mō te tūponotanga o te kino ki te kukune. Kāore tētahi kerēme whānui mō ngā “painga mō ngā wāhine” e whakakore i taua māharahara.
He pai mōu?
Kāore he painga mō te katoa kua whakaaturia e whakautu ana i tēnei pātai mō ia kaipānui. He mea nui katoa te putanga e whāia ana, te āhuatanga hauora, te ara tuku, me ērā atu rongoā. E rāhui ana te tapanga rongoā whakahau i te whakamahinga mō te hunga he hapa G6PD tō rātou, nā te tūraru o te anemia hemolytic, ā, e whakatūpato ana mō te mate serotonin taumaha i te taha o ngā rongoā serotonergic me ngā opioid. Pānuitia te tirohanga whānui mō ngā pānga taha me ngā āhuatanga e kore ai e tika te whakamahi i te taha o tētahi kerēme painga.
I mua i te whakaaro he tūtohutanga mōu ake tētahi rangahau pai, tautuhia te rōpū tangata, te whakataurite, te putanga i inea, me te wā aroturuki. Pātai mēnā e pā ana te putanga ki ngā tohu mate, ki te āhei ki ngā mahi o ia rā rānei, he inenga taiwhanga anake rānei. Kawea te rangahau tonu me ngā taipitopito o te hua ki tētahi kōrerorero haumanu, mā ēnei pātai hei ui mō te puru metilīni. Kaua e whakarerekē i ngā rongoā kua whakahaua kia taea ai tētahi hōtaka oranga whakamātautau.