Tuhinga
Ka tango te methylene blue i ngā konganuku taumaha, ka mahi rānei hei tango tāoke?
Ehara te methylene blue i te maimoatanga kua whakamanahia mō te tango konganuku taumaha i te tinana. Kāore ngā puna haumanu me ngā rangahau i tirohia mō tēnei tuhinga i tautohu i ngā taunakitanga tangata e whakaatu ana ka whakapiki whai tikanga te methylene blue i te whakakorenga o te mata, te mēkuri, te cadmium, te arsenic rānei, ā, ka whakapai hoki i ngā putanga o te paihana. He tepenga tēnei nō ngā taunakitanga i kitea, ehara i te taunakitanga kua whakakorea katoatia ngā pāhekoheko matū katoa ka taea.
E toru ngā kōrero rerekē ka whakakōpūtia nuitia ki raro i te kupu “tango tāoke”: he iti te poke o tētahi hua, ka whakarerekē tētahi matū i ngā urupare ahotea ā-pūtau, ā, ka tango tētahi maimoatanga i tētahi matū paitini i roto i te tangata. Kāore te taunakitanga mō tētahi e whakapūmau ana i ērā atu.
Ko te hua mā he putanga kounga
Ka tirohia e tētahi paewhiri konganuku taumaha te tauira hua kua tukuna. Tērā pea ka pūrongo i ngā rahinga o te mata, te mēkuri, te cadmium, me te arsenic, me ngā waeine, ngā tikanga, me ngā paepae pūrongo. He metarohe te arsenic, ahakoa ka whakaurua nuitia ki ngā paewhiri e kīia ana he whakamātautau konganuku taumaha.
Ko ngā tikanga tātari huānga a te FDA e whakaatu ana i te mahi tātari: te ine i ngā huānga motuhake i roto i tētahi rawa kua tautuhia mā ngā tukanga kua whakamanahia. Ki te raro iho tētahi hua i te paepae pūrongo, ko tōna tikanga kāore te taiwhanga i taea te pūrongo i tētahi rahinga kei runga ake i taua paepae i raro i aua tikanga. Ehara tēnā i te kī kāore rawa taua huānga i reira i runga i te pāngarau.
Mō te methylene blue, ka whakautu tēnei mēnā ka kawea mai e te tauira i whakamātauria tētahi poke kua inea. Kāore e kōrero mō te tango i te poke kua noho kē ki roto i te tinana. Kāore tētahi tiwhikete e whakaatu ana he iti te mata e taea te whakapūmau i te mahi here-mata, pērā anō kāore tētahi whakamātautau wai e whakapūmau i te āhua o te mahi a tētahi rongoā.
Ka whakamārama tā mātou aratohu mō ngā konganuku taumaha, Azure B, me ētahi atu poke o te methylene blue he aha hoki ngā pātai kounga kāore e whakautua e tētahi paewhiri huānga. Me whai taunakitanga tātari rerekē mō te tuakiri hua, ngā poke e pā ana ki te waikano, me ngā poke huānga.
He aha rawa ngā mea e hiahiatia ana kia tango konganuku?
Ko te chelation he tukanga e here ai tētahi matū ki tētahi katote konganuku. I roto i te maimoatanga hauora, ko te pātai whai take mēnā ka āwhina taua pāhekoheko i te tinana ki te whakakore i te konganuku e hāngai ana, me ngā tūraru e whakaaetia ana. Ko te here i roto i te ipu whakamātautau anake kāore e taea te whakapūmau ka tae tētahi matū ki te kiko tika, ka pupuri tonu i te konganuku i te wā e kawea ana, ka puta rānei he painga haumanu.
Ko te whakamārama a te FDA mō te chelation hauora e wehe ana i ngā maimoatanga whakahaunga e tirotirohia ana e te ngaio hauora i ngā hua kāore anō kia whakamanahia e hokona ana mō te tango tāoke i te kāinga. E kī ana kāore he hua chelation kua whakaaetia e te FDA mō te whakamahi hoko-noa kāore he whakahaunga.
Ki te kerēme pono te tango konganuku mā te methylene blue, me whakaingoa te konganuku, me tautohu te pānga ki taua matū, me tautuhi te hanga me te ara tuku, me whai rōpū whakatairite tika, ā, me ine i ngā huringa i roto i te wā. Me wehewehe ngā kairangahau i te pikinga o te whakakorenga i te nekehanga anō o te konganuku i waenga i te toto me ngā kiko, i te hekenga rānei o te pānga e haere tonu ana. He mea nui ngā putanga hauora me ngā pānga kino, ā, me whakaaro tahi ki ngā uara taiwhanga.
Kāore te kōrero “e tautoko ana i ngā ara tango tāoke” e whakarato i aua inenga kua ngaro. Waihoki kāore tētahi tikanga here e pā ana ki te whanariki kua whakapaetia mai i te hanganga o tētahi rāpoi ngota e whakarato i aua inenga.
Ripanga kerēme-ki-te-taunakitanga
Whakamahia tēnei ripanga hei tautohu he aha rawa tā tētahi pūrongo e ine ana i mua i te whakaae ki te kerēme e whai ana.
| Kerēme, kitenga rānei | Taunakitanga e aro ana ki taua mea | He aha kāore e taea te whakapūmau mā taua taunakitanga anake |
|---|---|---|
| “He iti te poke konganuku taumaha o tēnei puranga” | Ngā hua huānga kua herea ki te puranga, ngā waeine, ngā paepae pūrongo, te tuakiri tauira, me tētahi tikanga tika kua whakamanahia | Te tango konganuku i te tangata; te kore rawa o ētahi atu poke katoa |
| “Ka whakaiti te methylene blue i te ahotea hāora” | Ngā inenga pūtau, kararehe rānei kua whakahaerehia mō ngā paearu redox kua tautuhia, me ngā mana whakamātautau tika | Te here konganuku, te pikinga o te putanga konganuku, te whaihua rānei o te maimoatanga ki te tangata |
| “Ka here tētahi konganuku i roto i tētahi whakamātautau taiwhanga” | Ngā inenga here tika i raro i ngā tikanga matū kua whakatakotoria | Te here pūmau i roto i te tinana, te kawe haumaru, te whakakorenga rānei |
| “Kei te whakaputa atu te tinana i te nui ake o te konganuku” | Ngā inenga motuhake-konganuku kua whakamanahia, me te wā kohikohi tika, ngā whakatairite, me te whakamāoritanga | I reira tonu te paihana, kua heke te tapeke kawenga kino i ngā kiko, kua pai ake rānei te hauora |
| “Ka tango tāoke konganuku taumaha te methylene blue” | Ngā taunakitanga maimoatanga tangata e hono ana i te pānga, te wawaotanga, te nekehanga o te konganuku, ngā putanga whai tikanga, me ngā pānga kino | Kāore tēnei kerēme whānui i whakapūmautia e ngā taunakitanga i kitea mō tēnei tuhinga |
| “I huri te mimi hei kikorangi, hei kākāriki rānei” | Ngā taunakitanga o te tae nā te waikano | He inenga o te tangohanga o te mata, te mēkuri, te arsenic, te cadmium rānei |
He āwhina pānui-taunakitanga te ripanga, ehara i te kawa whakamātautau, maimoatanga rānei.
Kāore ngā pānga ārai hāora e ine i te whakakorenga konganuku
Ka whai wāhi te methylene blue ki ngā tauhohenga hāora-whakaiti. Nā reira ka taea e tētahi whakamātautau te tirotiro me pēhea tana whakarerekē i te urupare a tētahi pūtau ki te wharanga, me te kore e whakaatu ka tangohia e ia te pūtake o taua wharanga.
Hei tauira, i tirohia e te rangahau 2009 Striatal neuroprotection with methylene blue ngā kiore i whakawhiwhia ki te tāoke mitochondrial rotenone tika atu ki tētahi wāhanga o te roro, me te methylene blue i tukuna ā-rohe, me te kore rānei. I aromatawai ngā kairangahau i te rahi o te wharanga, te pākia hāora, te ahotea hāora, me te whanonga nekeneke. Ko te whakamarutanga i pūrongotia e pā ana ki te wharanga kiko whakamātautau. Ehara te rotenone i te konganuku taumaha, ā, ehara tēnei i te whakamātautau tangata mō te putanga konganuku.
Kei reira hoki tētahi pepa 1980 mō te ngohe whākōkī i ngā kiore kua pāngia e te paihana mata. E tautohu ana tana pūkete PubMed i taua kaupapa whakamātautau, engari kāore he whakarāpopototanga. Kāore te pūkete anake e taea te whakapūmau i tētahi pānga maimoatanga, te tango konganuku, tētahi tūtohutanga mō te tangata rānei. Kāore e ranea tētahi taitara e mau ana i te kupu “lead poisoning” hei taunakitanga mō tētahi kerēme tango tāoke ā-ipurangi.
Ka hāngai ēnei wehewehenga puta noa i ngā taunakitanga tangata mō ngā painga o te methylene blue. Ka whakarōpū te whare pukapuka rangahau i ngā rangahau mā ō rātou taupori me ō rātou paearu mutunga tūturu.
E rua ngā ara poto whakapohehe
Tuatahi, ehara te maimoatanga o te methemoglobinemia i te chelation konganuku. Ko ngā mōhiohio whakahaunga mō te PROVAYBLUE ā-iaia e whakamārama ana i te mahi a te methylene blue ki te huri i te rino hemoglobin mai i te āhua ferric ki te āhua ferrous. Ka huri te āhua hāora o te rino, engari ka noho tonu hei wāhanga o te hemoglobin. Kāore tēnei e whakaatu ana i te tangohanga o te rino, o ētahi atu konganuku rānei i te tinana.
Tuarua, i roto i ngā rangahau taiao mō te “tango”, ka huri kē pea ngā tūranga e whakapaetia ana e ngā kaipānui. Ko tētahi pepa e tapaina ana Removal of mercury and methylene blue from aqueous solution e rangahau ana i tētahi rauemi whakapiri graphene-oxide kua whakarerekētia ā-mahi. Ko te mēkuri me te methylene blue ngā matū e tangohia ana i te wai. Ehara te methylene blue i te maimoatanga e tango ana i te mēkuri i tētahi tūroro.
Ki te whakapae koe kua pā tūturu koe ki tētahi matū
Tīmata ki te matū, te pūtake, te wā, me te ara i pā ai. Kawea te ipu hua, ngā mōhiohio wāhi mahi, tētahi pūrongo taiwhanga e hāngai ana rānei ki tētahi rata, ratonga paihana rānei. Ko te kōwhiringa me te whakamāoritanga o ngā whakamātautau ka whakawhirinaki ki te konganuku e whakapaetia ana me ngā āhuatanga o te pānga.
Kaua e tango i tētahi chelator kia puta ai he whakamātautau mimi pai. Ko te tūranga a te American College of Medical Toxicology mō te whakamātautau mimi kua whakaohohia e whakamārama ana ka taea e ngā chelator te whakapiki i te putanga konganuku ki ngā tāngata kua paihana, kāore rānei i paihana. Mā te whakatairite i aua hua ki ngā awhe tohutoro noa kāore i whakaohohia ka puta pea he tātaritanga whakapohehe me te maimoatanga kāore e hiahiatia.
Kei te methylene blue anō hoki ōna ake pānga taha me ngā āhuatanga e kore ai e tika te whakamahi, tae atu ki ngā pāhekoheko rongoā hira me ngā tūraru mō te ngoikoretanga G6PD. Ko te māuiui i muri i te tango i te methylene blue ehara i te taunakitanga kei te nekehia ngā konganuku.
Mō tētahi paihana ohotata e whakapaetia ana, whakapā wawe ki tētahi ratonga paihana. Ko ngā tohutohu ohotata a Poison Control e whakahau ana kia rapua tonutia he āwhina ohotata mō te hinga, te hopukanga, te uaua ki te manawa, te kore rānei e taea te whakaoho. I te United States, ko te nama Poison Control ko 1-800-222-1222, ā, ko te nama ohotata ko 911; i wāhi kē, whakamahia ngā ratonga ā-rohe. Kaua e whakaroa te aromatawai kia whakamātau ai i tētahi tikanga tango tāoke methylene blue.