I-Methylene Blue: Imibuzo Yodokotela Wakho

Umbuzo owusizo kakhulu wokuqala uqondile: “Ngifuna usizo ngale nkinga, futhi ngibone kunconywa i-methylene blue. Ingabe ubufakazi buyasebenza esimweni sami?” Lokho kunikeza uchwepheshe wakho wezokwelapha umgomo azowuphenya kanye nesimangalo azosihlola. Ukubuza kuphela ukuthi i-methylene blue “yinhle” yini kushiya kokubili kungacacile.

Letha ilebula lomkhiqizo oqondile, uhlu lwamanje lwemithi nezithasiselo zokudla, kanye nomthombo wesincomo. Vula iphepha elilodwa lokuhlela ingxoxo nochwepheshe wezokwelapha bese uliphrinta ngaphambi kokubonana naye. Linikeza indawo yokubhala ulwazi nezinqumo. Ukuligcwalisa akuqinisekisi ukuthi umkhiqizo ukufanele.

1. Chaza inkinga ngaphambi kokuxoxa ngomkhiqizo

Bhala umusho owodwa ngalokho ofuna ukukushintsha. “Ngiyalahlekelwa umkhondo wemisebenzi emsebenzini” kunikeza ulwazi oluningi kunokuthi “Ngifuna ubuchopho bami busebenze kangcono.” Faka nokuthi inkinga yaqala nini, ukuthi iyashintsha yini, nokuthi ikuvimbela ekwenzeni ini. Uma usuvele unesifo esixilongiwe, sibhale ngokwehlukana nezimpawu ezingakahlolwa.

Buza: “Ingabe lokhu kudinga ukuhlolwa okwengeziwe ngaphambi kokuba sixoxe ngokwelashwa?” Isincomo somkhiqizo singenza ingxoxo iqale sekweqiwe izinyathelo ezibalulekile, ngemuva kokucabanga ukuthi imbangela yenkinga iyaziwa. Uchwepheshe wakho wezokwelapha kungase kudingeke aqale aphenye uphawu, abuyekeze ukwelashwa osuvele ukuthola, noma acacise umgomo.

Ukubeka okukukhathazayo ngokubaluleka nokuletha amarekhodi afanele kuhambisana nesiqondiso se-National Institute on Aging sokulungiselela ukubonana nodokotela. Beka umbuzo obaluleke kakhulu phezulu ekhasini lakho.

2. Cacisa lokho okuhlongozwayo

“I-methylene blue” yigama lento, hhayi elokwelashwa okuphelele. Thatha izithombe zengaphambili nengemuva lesiqukathi, kuhlanganise nezithako, ukugxila kwento, umkhiqizi, ukusetshenziswa okuhlosiwe, nenombolo yeqoqo. Bhala indlela yokuyisebenzisa ehlongozwayo, njengokuyiphuza noma ukuyinikezwa emtholampilo, ngaphandle kokuzama ukuguqula imiyalelo yomthengisi ibe uhlelo lwakho siqu lokuyisebenzisa.

Ulwazi lwase-U.S. lokunquma ukusetshenziswa kwe-PROVAYBLUE luchaza umuthi onikezwa ngencwadi kadokotela, ofakwa emthanjeni, wokwelapha i-methemoglobinemia etholwe kamuva kubantu abadala nasezinganeni. Lelo lebula alifakazeli inzuzo yebhodlela elithengiselwa abathengi ekukhumbuleni, emandleni, noma komunye umgomo ohlongozwayo.

Cela uchwepheshe wakho wezokwelapha acacise ukuthi yimuphi umkhiqizo nokusetshenziswa okuxoxwa ngakho ngempela. Uma umthengisi ethi “usezingeni lemithi,” letha imibhalo esekela lokho bese ubuza ukuthi ifakazela ini. Ukubuyekezwa kwekhwalithi yomkhiqizo okuwusizo kwehlukanisa ukuqinisekiswa kokuthi into iyini nokuhlolwa kwayo ebufakazini bokwelapha umuntu.

3. Letha uhlu oluphelele lwemithi

Faka imithi enikezwa ngencwadi kadokotela, imikhiqizo etholakala ngaphandle kwencwadi kadokotela, amavithamini, amakhambi, nezithasiselo zokudla. Faka umthamo owuthathayo njengamanje, izikhathi owuthatha ngazo, ukusetshenziswa ngezikhathi ezithile, nezinguquko zakamuva. Letha iphakethe uma izithako zomkhiqizo oxube izinto eziningana zingacacile. Cela usokhemisi abuyekeze uhlu kanye nomkhiqizo oqondile we-methylene blue nendlela yokuwusebenzisa ehlongozwayo.

Kunesizathu esiqondile sokwenza lolu hlu luphelele. Izixwayiso ze-PROVAYBLUE ngokusebenzisana neminye imithi zichaza isifo sokweqisa kwe-serotonin esingabulala lapho isetshenziswa nemithi esebenza ku-serotonin nama-opioid; ziphinde zibalule i-dextromethorphan, isithako esikweminye imithi yokukhwehlela. Ngakho umuthi osetshenziswa ngezikhathi ezithile kuphela nawo ungabaluleka. Lezi zibonelo azilona ukuhlolwa okuphelele kwakho konke ukusebenzisana kwemithi.

Ungayeki umuthi owunqunyelwe noma uziqambele isikhathi sokulinda ukuze ukwazi ukusebenzisa i-methylene blue. Cela lowo okunqumele umuthi nosokhemisi baxazulule noma yiziphi izinguquko ezihlongozwayo. Incazelo yethu ye-methylene blue nokusebenzisana kwayo nemithi ingakusiza ulungiselele amagama ozowasebenzisa kuleyo ngxoxo.

4. Buza ukuthi yimuphi umlando odinga ukubuyekezwa

Letha imininingwane efanele yezifo ezixilongiwe, ukungezwani komzimba, ukusabela kwangaphambilini, nemiphumela yokuhlolwa etholakalayo. Yisho lokho ongakwazi kunokuthatha ukuntuleka kolwazi njengempendulo ekuqinisekisayo ukuthi akukho okukhathazayo.

Ilebula lomuthi onikezwa ngencwadi kadokotela lithi i-PROVAYBLUE akufanele isetshenziswe uma kune-G6PD deficiency ngenxa yengozi ye-anemia ebangelwa ukubhidlika kwamangqamuzana egazi abomvu, noma uma kunokungezwani okukhulu nomuthi. Liphinde likhulume ngokukhulelwa, ukuncelisa, nokungasebenzi kahle kwezinso noma kwesibindi. Buza ukuthi yiziphi izingxenye zomlando wakho ezidinga ukuhlolwa nokuthi imiphumela ekhona yanele yini.

Lena yingxoxo ngokuthi umlando wakho ubaluleke kanjani ekwelashweni, hhayi uhlu lwamabhokisi okuthi uma esemakiwe lukunike imvume yokuqhubeka. Uchwepheshe wezokwelapha kufanele ahumushe umlando kanye nenhloso, umkhiqizo, indlela yokuwusebenzisa, nokunye ukwelashwa.

5. Letha isimangalo esisodwa nocwaningo olusisekelayo

Gcina isihloko sephepha locwaningo, isixhumanisi noma i-DOI, nomusho othile ofuna uhlolwe. Isithombe-skrini segrafu esingenayo incazelo yayo, izindlela zocwaningo, noma imininingwane yabantu ababecwaningwa ngokuvamile sishiya umbuzo obalulekile ungaphenduliwe: yini ngempela eyahlolwa?

Sebenzisa imibuzo elandelayo ukuze ugcine ingxoxo igxile odabeni. Yakhelwe esiqondisweni se-NCCIH sokuhumusha ucwaningo lwezempilo.

Okufanele ukubuze	Kungani impendulo ishintsha isinqumo
Ingabe lokhu kwahlolwa kubantu abanesimo esifana nesami?	Okutholwe elabhorethri noma eqenjini leziguli elehlukile kungase kungawuphenduli umbuzo wakho wokwelashwa.
Ingabe ucwaningo lwahlola lokhu kwakheka komkhiqizo nale ndlela yokuwusebenzisa?	Ukuba negama lesithako elifanayo akwenzi izindlela ezimbili zokwelapha zilingane.
Yini eyaba ngcono, futhi yaba ngcono ngezinga elingakanani?	Umphumela wokuhlolwa ungase ube nencazelo ehlukile ekusebenzeni kangcono ekuphileni kwansuku zonke.
Yikuphi ukwelashwa okwasetshenziselwa ukuqhathanisa?	Ukuba ngcono ngokuhamba kwesikhathi kukodwa akubonisi ukuthi indlela yokwelapha yikho okwabangela lokho.
Abahlanganyeli balandelelwa isikhathi esingakanani?	Ukubhekwa isikhathi esifushane akukwazi ukufakazela inzuzo ehlala isikhathi eside noma ukuphepha kwesikhathi eside.
Yini esangaziwa?	Ukungaqiniseki kufanele kucace ngaphambi kokunquma ukuthi yini ezokwenziwa ngokulandelayo.

Khetha imibuzo emibili ehlobene kakhulu nesimangalo. Akudingeki ubuyekeze yonke imibhalo yocwaningo ngaphambi kokucela usizo.

6. Qhathanisa ezinye izindlela bese nivumelana ngesinyathelo esilandelayo

Buza ukuthi yiziphi izindlela ezaziwayo ezibhekana nomgomo ofanayo, ukuthi yikuphi ukuhlolwa okwengeziwe okungashintsha isinqumo, nokuthi kunengqondo yini ukungenzi lutho olusha ngenkathi kuqoqwa ulwazi. Incazelo ye-FDA yokunquma ukusetshenziswa komuthi ngaphandle kokusetshenziswa okugunyaziwe yenza umehluko obalulekile: ochwepheshe bezokwelapha bangase banqumele umuntu umuthi ogunyaziwe ngenhloso engakagunyazwa uma kufanele ngokwezokwelapha, kodwa i-FDA ayikaqinisekisi ukuphepha nokusebenza kwawo kulokho kusetshenziswa okungagunyaziwe. Buza ukuthi yini esekela ukusetshenziswa okuhlongozwayo esimweni sakho.

Uma ubufakazi bungaqinisekile, cela impendulo eqondile: “Ingabe ukungaqiniseki kumayelana nokuthi uyasebenza yini, ukuthi uphephile yini kimi, noma ukuthi lo mkhiqizo uhambisana yini nocwaningo?” Igebe ngalinye lidinga isinyathelo esilandelayo esehlukile. Ukukhathazeka ngokuphepha kudinga ukubuyekezwa; ukungabi khona kobufakazi benzuzo akulungiseki ngokukhetha ilebula elibukeka lihlaba umxhwele kakhulu.

Ngaphambi kokuhamba, bhala isinyathelo enivumelene ngaso, ukuthi ubani onesibopho, nokuthi uzoyithola nini impendulo. Uma kuhlongozwa ukwelashwa, buza ukuthi inzuzo nokulimala kuzohlolwa kanjani, ukuthi ubani ozosingatha izimpawu ezintsha, nokuthi yini engaholela ekutheni uchwepheshe wezokwelapha akucabangele kabusha. Uma kunganconywa ukwelashwa, bhala isizathu nohlelo lokubhekana nokukhathazeka kwakho kwasekuqaleni. Ukubonana kuyasiza uma uhamba unempendulo ngalokho kukhathazeka kanye nohlelo olucacile lokulandelela, kungakhathaliseki ukuthi i-methylene blue iba yingxenye yohlelo noma cha.