Chinyorwa
Kukuvadzwa nemethylene blue nekutora yakawandisa: zvinoda kuongororwa nekukurumidza
Kana uchifungidzira kuti munhu asangana nemethylene blue nenzira inogona kukuvadza zvakanyanya, tsvaga kuongororwa nenyanzvi pakarepo. Usamirira zviratidzo kana kuverenga uwandu hwekudarika hunonzi hwakachengeteka. Kana munhu akadonha, akaita pfari, achinetseka kufema, kana asingagoni kumutswa, fonera nhamba yekubatsirwa nechimbichimbi yemunharaunda yako. MuUnited States, fonera 911 pazviitiko izvi zvechimbichimbi; mune zvimwe zviitiko, kurumidza kubata Poison Control pa 1-800-222-1222 kuti uwane mazano pamusoro pekusangana nechinhu ichi. Zviratidzo izvi zvinoda rubatsiro rwechimbichimbi zvinobva pamazano eNational Capital Poison Center erubatsiro rwekutanga.
Mashoko ekuti “kukuvadzwa nechepfu yemethylene blue” anogona kureva zvinhu zviviri zvakasiyana: kukuvadzwa nechepfu uko murapi anoshandisa methylene blue, uye kukuvadzwa kunokonzerwa nemethylene blue pachayo. Kuvhiringidza zvinhu izvi kunogona kuita kuti munhu atore zvimwe zvechinhu ichocho chinotoda kuongororwa.
Mushonga unorwisa chepfu pachirwere cheropa chakananga
Hemoglobin iri mumasero matsvuku eropa inoendesa oxygen kunyama dzemuviri. Pachiitiko chemethemoglobinemia, chikamu chakakura zvisina kujairika chinenge chiri methemoglobin, zvichikanganisa kuendeswa kweoxygen. Tsananguro yeMedlinePlus pamusoro pemethemoglobinemia inosiyanisa mhando dzinogarwa nhaka nechirwere chinowanikwa nokusangana nezvinhu zvakaita semimwe mishonga kana makemikari. Zviratidzo zvinogona kusanganisira ganda rine ruvara rwebhuruu, kutadza kuwana mweya wakakwana, uye kuchinja kwekusvinura.
Methylene blue inopiwa nemutsinga inoshandiswa kurapa methemoglobinemia isina kugarwa nhaka. Chinangwa chayo ndechekubatsira kudzorera hemoglobin inoshanda. Uku kushandiswa pakurapa chirwere chakananga, kwete mushonga wekukuvadzwa nechepfu kwese kana kwese kunoonekwa ganda rine ruvara rwebhuruu. Gwaro remethylene blue pakurapa methemoglobinemia rinotsanangura mamiriro ekurapa aya.
| Mubvunzo | Kushandiswa kurwisa chepfu | Kusangana nayo kunofungidzirwa kuti kunokuvadza |
|---|---|---|
| Dambudziko rekutanga nderei? | Methemoglobinemia isina kugarwa nhaka, yakaonekwa uye yakaongororwa nevarapi | Kusangana nemethylene blue kunogona kukuvadza |
| Methylene blue ine basa rei? | Mushonga wakasarudzwa kurapa dambudziko chairo | Chinhu icho varapi vanofanira kufunga kuti chinogona kunge chiri kukonzera kurwara |
| Ndeapi mashoko akakosha? | Chirwere chakaonekwa, mamiriro emurwere, kuti muviri uri kupindura sei kurapwa | Chigadzirwa, nzira yekusangana nacho, uwandu, nguva, zviratidzo, nemimwe mishonga |
| Muverengi anofanira kuitei? | Tevedzera mirayiridzo yeboka rinorapa | Kurumidza kubata nzvimbo inopa rubatsiro nezvechepfu kana rubatsiro rwechimbichimbi |
Musiyano uyu unoramba uchikosha kunyange kana kusangana kwekutanga nechinhu ichi kwakaitwa nemaune uye kuchitsanangurwa sekutora chekuwedzera mukudya kana kurapwa kwekuvandudza utano. Chikonzero chekutora chinhu hachiratidzi kuti kusangana nacho kwakachengeteka.
Kukuvadzwa nechepfu kunogona kuratidzika sei
Mazano eNational Capital Poison Center pamusoro pemethylene blue anotsanangura kusvotwa, kutemwa nemusoro, dzungu, uye kuchinja ruvara kuva rwebhuruu, pamwe chete nechinhu chinoratidzika kupesana chekuti kuipiwa kwakawandisa kunogona kukonzera methemoglobinemia. Weti yebhuruu yoga hairatidzi kuti kusangana nechinhu ichi kwanyanya zvakadii. Saizvozvowo, miromo ichangotanga kuva yebhuruu pamwe nekutadza kuwana mweya wakakwana hazvifaniri kungonzi kusvibiswa nedhayi.
Kukuvadzwa kunobva paserotonin chimwe chinonetsa, kunyanya kana paine mishonga inopindirana. Fivha, kusagadzikana kana kuvhiringidzika, kudikitira, kurova kwemwoyo nekukurumidza, uye kuoma kwemhasuru zvinogona kuitika pamwe chete. Zviratidzo zvitsva mushure mekusangana nechinhu ichi zvinoda kuongororwa nekukurumidza; muverengi haafaniri kuedza kuzvisarudzira chirwere achishandisa rondedzero yezviratidzo.
Mashoko ekunyorera PROVAYBLUE murwere anotsanangurawo hemolysis, zvinoreva kuparara kwemasero matsvuku eropa, uye kusawirirana nemushonga kwakakomba. Kushomeka kweG6PD mamiriro anoita kuti mushonga uyu usafanira kushandiswa nokuda kwenjodzi yeanemia inokonzerwa nekuparara kwemasero matsvuku eropa. Anemia inogona kuoneka zuva rimwe chete kana kupfuura mushure mekurapwa. Kurwadziwa muchipfuva, kufema kune muridzo, kana kuderera kweoxygen mumuviri ndezvimwe zvezvakataurwa kuti zvinokonzerwa nekuipiwa kwakawandisa. Naizvozvo, kunzwa zvakanaka pakarepo mushure mekusangana nechinhu ichi hakuratidzi kuti matambudziko haazouyi gare gare.
Mashoko echigadzirwa anoyambira nezvemishonga inokanganisa serotonin nemaopioid, kusanganisira njodzi kana paine dextromethorphan. Ipa nyanzvi rondedzero yakazara yemishonga. Tsananguro yekushomeka kweG6PD nemethylene blue inotsanangura chimwe chikonzero chinoita kuti mamiriro emunhu mumwe nemumwe ave akakosha.
Nei nzira yekusangana nayo ichichinja mubvunzo
Kumedza mushonga uri mumvura, kubayiwa jekiseni, kusaswa muziso, uye kufema upfu zvakasiyana pakutsanangura kusangana nechinhu ichi. Taura nzira yakaitika chaizvo, kunyange kana yakasiyana nemashandisirwo akarongerwa chigadzirwa. “Madonhwe maviri” haana kukwana kana bhodhoro rakashandiswa risingazivikanwi; “sirinji imwe” haina kukwana pasina kuziva kusimba kwemushonga neuwandu hwemvura yacho. Gwaro rekududzira zviyero zveuwandu hwemethylene blue rinotsanangura misiyano iyoyo yekuyera.
Tsananguro yePoison Control yemazwi anoshandiswa pakusangana nechinhu nekutora chakawandisa inosiyanisa zvinhu zvinobatsira: kusangana nechinhu kunoreva kubatwa nechinhu chinogona kukuvadza, asi kukuvadzwa nechepfu kunoreva zvinokuvadza zvaitika. Kufona pamusoro pekusangana nechinhu hakudi kuti utange waratidza kuti kukuvadzwa nechepfu kwaitika. Nzira yekusangana nacho, uwandu, nguva, nezviratidzo zvinobatsira nyanzvi kusarudza kuti kuongororwa kupi kunodiwa.
Kana chasasa muziso, tanga kugeza nemvura ine tembiricha yemumba pakarepo kwenguva ye15–20 minutes uye bvisa malenzi anoiswa mumaziso. Kana chasvibisa ganda, bvisa zvipfeko zvachabata uye geza nemvura inoyerera kwenguva ye15 minutes kana kupfuura. Mushure mekuchifema, enda kune mweya mutsva usingapindi munzvimbo isina kuchengeteka. Wana mazano enzvimbo inopa rubatsiro nezvechepfu paunenge uchiita rubatsiro urwu rwekutanga kana mushure marwo. Usazviitisa kurutsa mushure mekumedza chigadzirwa. Rubatsiro rwekutanga harufaniri kunonotsa rubatsiro rwechimbichimbi pazviratidzo zvakakomba.
Rondedzero yemashoko pamusoro pekusangana nechinhu ichi
Shandisa zvinotevera kukutungamirira paunenge uchifona. Usanonotsa kufona kuti utange wazadza tafura. Verenga zviri pamavara echigadzirwa sezvazvakanyorwa; kana usina chokwadi nezverimwe shoko, nyora kuti harizivikanwi pane kufungidzira. Pikicha inogona kuchengetedza mashoko echigadzirwa pasina kudururira kemikari mune chimwe chigadziko.
| Mashoko ekutaura | Zvinofanira kunyorwa kana kuverengwa zvinonzwika |
|---|---|
| Munhu nemamiriro ake iye zvino | Zera; uremu hunofungidzirwa kana huchizivikanwa; kuti akamuka uye ari kupindura here kana kuti kwete; kuti ari kufema zvakanaka here kana kuti kwete; nzvimbo yaari iye zvino |
| Chigadzirwa chaicho | Zita nemugadziri; kusimba kwemushonga nezviyero sezvakadhindwa; zvinoumba chigadzirwa; saizi yebhodhoro; mashandisirwo akarongerwa; pikicha yemashoko echigadzirwa kana chigadziko chacho chepakutanga |
| Chiitiko chekusangana nechinhu ichi | Chakamedzwa, chakabayiwa, chakasvika muziso, paganda, kana chakafemwa; nguva kana fungidziro yepedyo zvikuru; chiitiko chimwe chete kana kusangana nacho kakawanda; uwandu hunofungidzirwa uye kuti hwakayerwa sei |
| Zviratidzo nekuchinja | Chakatanga kuitika; nguva yakatanga zviratidzo; kuti zviri kuwedzera here; kurutsa, kuchinja kwekufema, kuvhiringidzika, fivha, kana zviratidzo zvemhasuru |
| Mamiriro eutano nezvakaitwa | Mishonga, zvekuwedzera mukudya, nezvimwe zvinhu zvakatorwa; kushomeka kweG6PD kunozivikanwa; pamuviri; chirwere cheitsvo kana chechiropa; kugeza kana zvimwe zvakatomboitwa |
Kana uwandu husina chokwadi, tsanangura uchapupu: semuenzaniso, “Bhodhoro rakanga rakavhurika uye imwe mvura yacho haisisimo; hapana akaona ichimedzwa.” Izvi zvinobatsira kupfuura kushandura kusava nechokwadi kuita uwandu hwemushonga hunotaridzika sehwechokwadi. Chengeta chigadziko chacho chiripo kuti boka renyanzvi richione kana zvakachengeteka kuita izvozvo.
Hapana nzira yekushandisa mushonga unorwisa chepfu kumba
Usatora imwe methylene blue, marasha akagadzirirwa kurapa chepfu, kana chimwe chinhu kuti “upedze simba” rechinhu chakasangana nemuviri pasina kutungamirirwa nenyanzvi. Mazano eNHS pamusoro pekukuvadzwa nechepfu anokurudzira rubatsiro rwekurapa rwepakarepo kana kukuvadzwa nechepfu kuchifungidzirwa, anoyambira kuti zviratidzo zvinogona kunonoka kuoneka, uye anoti munhu haafaniri kuitiswa kurutsa kana kupiwa chikafu kana zvekunwa achimirira rubatsiro. Kurapwa nekutariswa kwemurwere zvinoenderana nechinhu chakatorwa uye zvinoonekwa pakuongororwa.
Mashoko emethylene blue anoti mushure mekuipiwa kwakawandisa panofanira kutariswa kukuvadzwa kwemwoyo nemapapu, kweropa, uye kwetsinga, pachipiwa rubatsiro rwekutsigira mashandiro emuviri sezvinodiwa. Anocherechedzawo kuti methylene blue inogona kukanganisa zviyero zvinoratidzwa nemudziyo unoyera oxygen muropa uchishandisa kurova kwetsinga. Chiyero cheoxygen chinotorwa kumba hachigoni kutsiva kuongororwa.
Pane chikonzero chine chokuita nemashandiro ayo chinoita kuti kuverenga madonhwe kusagona kugadzirisa nyaya yenjodzi yekupindirana kwemishonga. Muongororo yaRamsay nevamwe ya2007 pamusoro peenzyme, methylene blue yakadzivisa kushanda kwehuman monoamine oxidase A yakacheneswa, enzyme ine chekuita nekushandurwa kweserotonin mumuviri. Aya aiva maedzo emurabhoritari, kwete muedzo waitara uwandu hwakachengeteka hwekutora nemuromo kana muganhu wekutora zvakawandisa. Mazano ekurapa pamusoro pekusangana nechinhu ichi anofanira kufunga nezvechigadzirwa chaicho, nzira yekusangana nacho, murwere, uye zvimwe zvinhu zvaibatanidzwa.