Chinyorwa
Methylene blue inorapa UTI here? Zviratidzo, utachiona, uye mishonga yakasanganiswa
Methylene blue yoga haisi nzira yakasimbiswa yekurapa kutapukirwa nemabhakitiriya munzira dzeweti. Kuva kwayo mumushonga wakasanganiswa wezvinetso zveweti hakuratidzi kuti bhodhoro remethylene blue yoga richaporesa kuzvimba kwedundira, kudzivirira kudzokorora kwacho, kana kurapa utachiona hweprostate. Chidzidzo chekurapa chinokurukurwa pasi apa chakaedza mishonga yakasanganiswa, chikazowedzera maantibiotic.
Musiyano wokutanga unobatsira uri pakati pekunzwa zviri nani nekurapa chinokonzera dambudziko. Zvose zvinokosha. Mushonga unogona kuderedza kugwinha kwedundira mabhakitiriya achiripo; zviratidzo zvinogonawo kuramba zviripo kunyange kutapukirwa nemabhakitiriya kusisiri iko kunozvikonzera. Nhungamiro yeNIDDK yekurapa utachiona hwedundira inosiyanisa maantibiotic ekurapa utachiona hwemabhakitiriya nemishonga yemarwadzo, pamwe nekumwe kuongorora kana utachiona husingakwanisi kusimbiswa.
Zvinogona kusimbiswa nezviratidzo zvine chokuita neweti
Kunzwa kupisa paunenge uchiita weti, kuda kuita weti nokukurumidza, kuita weti kakawanda, uye kusagadzikana pasi pedumbu zvinogona kuitika paUTI. Zvisinei, zvinotsanangura zviri kunzwikwa nemunhu, kwete kuzivisa chinokonzera. Cystitis inoreva kuzvimba kwedundira; cystitis inokonzerwa nemabhakitiriya ndiyo imwe yezvinokonzera, asi interstitial cystitis/bladder pain syndrome idambudziko rakasiyana pakuongorora.
Kuongororwa kweutachiona hwedundira kunobatanidza nhoroondo yezveutano, kuongororwa kwemuviri, uye bvunzo dzakakodzera. Kuongorora weti kunogona kuona zvinhu zvakadai semasero machena eropa neropa. Bvunzo yekuotesa mabhakitiriya mumuweti inotsvaga kukura kwemabhakitiriya uye inogona kubatsira pakusarudza antibiotic. Bvunzo idzi dzinopindura mibvunzo yakasiyana, saka mashoko okuti “bvunzo yangu yeweti haina kuwana utachiona” anoda kujekeswa: ibvunzo ipi, yakaitwa riini, uye yakaitwa panguva ipi zvichienzaniswa nekurapwa kupi?
Zviratidzo zvinoramba zviripo pasinei nebvunzo dzisina kuwana utachiona zvinoda kucherechedzwa. Bvunzo yekuotesa mabhakitiriya isina kuawana haisi chikonzero chekufuratira marwadzo, asi marwadzo haasimbisewo kuti kune utachiona hwakavanda. Chirevo cheUrological Society of Australia and New Zealand chinobvuma kuti kuongorora kune miganhu uye chinokurudzira kuongororwa kunoenderana nemunhu mumwe nomumwe. Mhedzisiro inofanira kududzirwa pamwe chete nezviratidzo nezvimwe zvakawanikwa, kwete kuva chikonzero chokutanga kurapwa nemishonga inorwisa utachiona kakawanda pasina kutariswa.
Kudzikisa zviratidzo zvichienzaniswa nekurapa utachiona
Shandisa kuenzanisa uku paunenge uchiongorora zvinotaurwa nezvechigadzirwa kana kukurukura zvakaitika pakurapwa. Kunoparadzanisa zvakaonekwa nemhedziso yazvinogona kutsigira.
| Zvakaonekwa kana chinangwa chekurapa | Zvazvinogona kukuudza | Zvazvisingagoni kusimbisa zviri zvoga |
|---|---|---|
| Kudzikira kwekunzwa kupisa, kuda kuita weti nokukurumidza, kana kugwinha kwedundira | Zviratidzo zvadzikira, izvo zviri mhedzisiro inokosha | Kuti mabhakitiriya aivapo pakutanga kana kuti abviswa |
| Kuita kunorwisa mabhakitiriya pasi pemamiriro emurabhoritari | Chinhu chinokanganisa mabhakitiriya pasi pemamiriro akaedzwa | Kuti chigadzirwa chinonwiwa chinosvika zvakachengeteka pahuwandu hunoshanda munzira dzeweti dzemurwere |
| Bvunzo yekuotesa mabhakitiriya mumuweti isina kuawana | Hapana kukura kwemabhakitiriya kwaisvika pachiyero chinofanira kutaurwa kwakawanikwa pasi pemamiriro ebvunzo iyoyo | Chikonzero chokuti zviratidzo zvirambe zviripo, kana kuti chimwe chigadzirwa ndicho chakakonzera mhedzisiro yacho |
| Kurapwa kweUTI yemabhakitiriya kunotungamirirwa nenyanzvi yezveutano | Kurapwa kunonangana neutachiona hwakaongororwa, kuchiteverwa zvichienderana nemamiriro emurwere | Kuti chiitiko chose chinotevera chine chikonzero chimwe chete kana chinoda mushonga mumwe chete |
| Weti yebhuruu kana yegirini mushure memethylene blue | Dhayi inogona kuchinja ruvara rweweti | Kuurayiwa kwemabhakitiriya, kubudirira kwekurapa, kana kuyera kukomba kweutachiona |
Somuenzaniso, mumwe munhu anotanga piritsi remishonga yakasanganiswa oti manheru iwayo kugwinha kwadzikira. Iwayo mashoko anobatsira pamusoro pezviratidzo. Kuti zvitaurwe kuti methylene blue yaporesa utachiona, pane mimwe mibvunzo ichiripo: paiva neutachiona here, chii chimwe chaiva mupiritsi, maantibiotic akashandiswawo here, uye chii chakaitika pakuzoteverwa kwemurwere?
Nei mishonga yakasanganiswa yakasiyana
Chiratidzo cheUribel capsule paDailyMed chinotsanangura kudzikiswa kwezviratidzo zvekutsamwiswa kwenzira dzeweti. Zvinhu zviri mairi zvine mabasa akasiyana akataurwa:
| Chinhu chiri mumushonga | Basa rinotsanangurwa pachiratidzo checapsule iyi |
|---|---|
| Hyoscyamine | Inozorodza tsandanyama dzakatsetseka kuti ideredze kugwinha |
| Phenyl salicylate | Inoburitsa salicylate kuti idzikise marwadzo |
| Methenamine | Inoburitsa formaldehyde muweti ine asidhi, zvichiita kuti pave nekuita kunorwisa mabhakitiriya |
| Sodium phosphate monobasic | Inobatsira kuchengetedza asidhi muweti inodiwa kuti methenamine ishande |
| Methylene blue | Ine simba risina kunyanya kusimba rekuuraya utachiona; inogona kuchinja ruvara rweweti |
Chiratidzo ichi chinotaura pachena kuti FDA haina kubvumidza mashoko ari pachiratidzo kana kuona kuti chigadzirwa ichi chakachengeteka uye chinoshanda. Kunyorwa paDailyMed hakusi chitupa chekubvumidzwa. Misanganiswa inosiyana, saka tarisa pasuru yacho chaiyo pane kushandisa tafura iyi pachigadzirwa chose chine zita rakafanana. Nhungamiro yedu yemishonga yakasanganiswa yezvinetso zveweti ine methylene blue inotsanangura misiyano yezvigadzirwa.
Methenamine nemethylene blue zvinhu zvakasiyana. Kurudziro dzeNICE pamusoro peUTI inodzokorora dzinosanganisira methenamine hippurate senzira yokudzivirira kune vamwe varwere vakasarudzwa, mushure mokunge UTI ipi zvayo iripo yarapwa zvakakwana. Kurudziro iyoyo haisimbisi methylene blue senzira yokudzivirira, kana kuita kuti mushonga wakasanganiswa wokudzikisa zviratidzo ungotsiviwa nemethenamine hippurate.
Zvakanyatsoyerwa nechidzidzo chemishonga yakasanganiswa
Chidzidzo cha2020 chaGama nevamwe, chaigovera vatori vechikamu mumapoka zvisina kurongwa uye chisina kuita kuti vatori vechikamu nevatsvakurudzi vazive mushonga waipiwa, chakapinza vanhu vakuru 288 vaiva necystitis inodzokorora, vanenge vose vari vakadzi. Chakaenzanisa methenamine pamwe nemethylene blue zvainwiwa nemusanganiswa waiva nezvinhu izvozvo pamwe neacriflavine nebelladonna. Pakanga pasina boka raishandisa methylene blue yoga uye pasina boka raipiwa placebo.
Mhedzisiro huru yakayerwa yaiva kuvandudzika muchikamu chemibvunzo chaibata kuita weti zvakarongeka mushure memazuva matatu. Kuvandudzika kwakaitika mu69.4% ne72.2% zvemapoka acho, zvichitevedzana, pasina musiyano une kukosha kwehuwandu pakati pemapoka. Maantibiotic akasarudzwa zvichibva pabvunzo dzekuotesa mabhakitiriya akazowedzerwa kwemazuva matatu okupedzisira echidzidzo chemazuva matanhatu.
Naizvozvo chidzidzo ichi chinopa ruzivo pamusoro pezviratidzo zvenguva pfupi panguva yekurapwa nemishonga yakasanganiswa ichitariswa. Hachikwanisi kupatsanura zvakabatsirwa nemethylene blue, kuratidza kuti yoga inopedza mabhakitiriya, kana kusimbisa kudzivirira kwenguva refu. Nzira yacho yakashandiswa muchidzidzo haisi hurongwa hwekurapa kumba, uye zvakawanikwa hazvisimbisi kushanda kwayo pakuzvimba kweprostate kunokonzerwa nemabhakitiriya kunogara kwenguva refu.
Marwadzo edundira anoramba aripo, kuzvimba kweprostate, nematombo
Kana zviratidzo zvichidzokorora, kuongorora kunofanira kusiyanisa kutapukirwa kunodzokorora nedambudziko rinoita kuti zviratidzo zvirambe zviripo. Interstitial cystitis inoonekwa nekuongorora zviratidzo uye kubvisa zvimwe zvinogona kuzvikonzera, pachishandiswa nhoroondo yezveutano, kuongororwa kwemuviri, uye bvunzo sezvinodiwa. Haisi kuonekwa nokungoti bvunzo imwe yekuotesa mabhakitiriya haina kuawana.
Musiyano mumwe chete uyu unokosha kuvarume vane marwadzo munharaunda yechiuno, kurwadziwa pakuita weti, kana “prostatitis” inoratidzika seisingamboperi. NIDDK inosiyanisa kuzvimba kweprostate kunokonzerwa nemabhakitiriya nekuzvimba kweprostate kunogara kwenguva refu, umo utachiona husingawanzoonekwa. Chirwere chemarwadzo emunharaunda yechiuno anogara kwenguva refu chingada nzira yakasiyana neyekurapa utachiona hweprostate hwakasimbiswa. Zviratidzo zvine chokuita neweti kana kunzwa zviri nani kwenguva pfupi mushure momushonga hazvizivisi utachiona huri kukonzera dambudziko.
Zvinotaurwa pamusoro pematombo zvinoda humbowo hwazvo. Dombo risisawonekwi pakutora mufananidzo womukati memuviri gare gare hariratidzi kuti methylene blue yakarinyungudutsa, uye kuchinja kwemarwadzo hakuyeri zvinhu zvakaumba dombo kana ukuru hwaro. Kuongororwa nekurapwa kwematombo zvinoenderana nezvinhu zvinoratidza rudzi rwedombo racho. Chidzidzo chemishonga yakasanganiswa chiri pamusoro hachina kubatanidza vanhu vakanga vambova nematombo eitsvo. Hachipi humbowo hwekunyungudutswa kwematombo.
Huya nemashoko aya pakusangana nenyanzvi yezveutano
Shandisa runyorwa urwu kuti zviratidzo zvinodzokorora zvive nyore kuongorora. Nyora zvawaona usina kutotanga wafunga kuti chiitiko chose chinokonzerwa nemabhakitiriya.
- Nguva yakatevedzana yezviratidzo: zuva rokutanga, panonzwa marwadzo, kuti unoita weti kangani, fivha, ropa rinooneka, uye kana marwadzo achichinja dundira parinozara kana kubuda weti. Nyora nguva dzisina zviratidzo uye, kana zvakakodzera, marwadzo emunharaunda yechiuno kana ane chokuita nokubudisa urume.
- Mishumo chaiyo yebvunzo: kuongororwa kweweti, bvunzo yekuotesa mabhakitiriya, mhedzisiro yekuti mabhakitiriya anokanganiswa nemaantibiotic api, uye mifananidzo yomukati memuviri. Sanganisira mazuva uye kana sampuli dzakatorwa maantibiotic kana mishonga yezvinetso zveweti isati yashandiswa kana mushure mokushandiswa.
- Nguva yakatevedzana yekurapwa: mazita emaantibiotic nemishonga yezviratidzo, mazuva ayakashandiswa, shanduko dzakaonekwa, uye zvinokuvadza zvakaitika. Huya nemifananidzo yezviratidzo zvepasuru dzezvigadzirwa zvakasanganiswa uye chechero methylene blue yoga.
- Mashoko ezveutano nemishonga akakodzera: mukana wokuva nepamuviri, zvinetso zveitsvo, matombo akamboitika, kunetseka kubudisa weti yose mudundira, kusawirirana nezvimwe zvinhu, uye mishonga yose yakanyorerwa nachiremba nezvinowedzera pakudya. Mushumo wenyaya yemushonga unonwiwa wokuderedza marwadzo ane chokuita neweti wakatsanangura kukuvadzwa kunokonzerwa neserotonin nechigadzirwa chine methylene blue, zvichiita kuti kunyanya kukosha kuzivisa mishonga yekuora mwoyo nemimwe mishonga inokanganisa serotonin.
- Mubvunzo wokuzotevera: “Chii chinotsigira kuti pane utachiona pachiitiko ichi, chii chakanangana nekudzikisa zviratidzo, uye chii chinofanira kuitika kana zviratidzo zvikaramba zviripo?” Shandisa nhungamiro yakakura yemibvunzo yokubvunza nyanzvi yezveutano pamusoro pemethylene blue pakukurukura nezvemishonga chaiyo.
Bata nyanzvi yezveutano kana uchifungidzira utachiona hwedundira. Tsvaga rubatsiro rwechimbichimbi kana paine zviratidzo zvinogona kuratidza utachiona hweitsvo, zvinosanganisira fivha kana kudedera nechando, marwadzo emusana kana eparutivi, kana kurutsa. Kutadza kuita weti kunodawo kuongororwa nokukurumidza. Usamirira kuti dhayi kana mushonga wokudzikisa zviratidzo ushande mumamiriro aya.