Uribel, Uro-MP, me Urogesic Blue: he aha ēnei i kīia ai he rongoā whakakotahi

Ka tīmata tētahi tūroro ki te tango i tētahi kāpene kikorangi mō te mamae wera i te mimi me te hiahia ohorere ki te mimi. Ka kikorangi te mimi. Ina rerekē te ingoa waitohu kei te pounamu rongoā hou, ka puta he pātai whaitake i te tūroro: ko te waikano kikorangi rānei te wāhanga hohe, ā, he ōrite rānei te mahi a ngā hua katoa kei roto te methylene blue?

He hē taua whakaaro, ā, ka whakamārama te tapanga i te take. He rongoā whakakotahi te rongoā Uribel, a Uro-MP, me Urogesic Blue. Ko te methylene blue tētahi o ngā wāhanga maha, ā, e kīia ana i te tapanga he patu moroiti ngoikore, ehara i te maimoatanga katoa. Hei whakataurite i ēnei hua, pānuitia ia kai whakauru me tōna kaupapa whakamahi kua tuhia, kaua e aro noa ki te tae.

Kei DailyMed ngā hua e toru e kōrerotia ana i konei, hei hua rongoā kāore anō kia whakaaetia, me ngā tapanga nā ngā kaihanga i tuku. He mea nui taua tūnga. Ko te tikanga, ka whakaahua ngā tapanga i te hanganga o te hua e hokona ana, engari kāore ngā hua i whai i taua arotake whakaaetanga rongoā hou a te FDA e whāia ana e tētahi rongoā whakahaunga kua whakaaetia. Tirohia te tapanga o te rongoā kua tukuna ki a koe, kaua ko te ingoa whānau o te waitohu anake, i mua i te whakapae he ōrite.

He whakataurite i ngā kai whakauru o ia hua

E whakamahi ana te ripanga i ngā tapanga o nāianei nō te US. Ko ngā kaha mō Uribel me Uro-MP e hāngai ana ki ia kāpene, ā, ko ngā kaha mō Urogesic Blue e hāngai ana ki ia pire whai paninga.

Ka whakarārangi te tapanga Uribel o nāianei i tēnei huinga kai whakauru e rima, ā, ka whakaahua i ia mahi kua tuhia i runga ake nei. He ōrite ia kai whakauru o te tapanga Uro-MP o nāianei ki tō Uribel, he ōrite hoki ngā kaha; ko te āhua tote o te phosphate anake te mea e whakaahuatia rerekētia ana. E whakaahua ana te tapanga Urogesic Blue o nāianei i tētahi pire e whā ōna kai whakauru, he rerekē ngā kaha o te methenamine me te methylene blue, ā, kāore he phenyl salicylate i roto.

He kōrero motuhake hei aro māu i te pānui tapanga. E kī ana te wāhanga Whakaahuatanga o Uribel he 118 mg te methenamine, engari e whakaatu ana te ripanga kai whakauru kua hangarautia i taua whārangi DailyMed anō he 120 mg. Whakamahia te uara 118 mg o te Whakaahuatanga me te mōkihi mō te hanganga o ia kāpene. Me noho taua rerekētanga hei take ki te whakaū i te mōkihi kua tukuna, kaua hei kaha motuhake.

Te mahi kua tohua ki ia kai whakauru i te tapanga

Ko te methenamine te mea matua e mahi ana hei patu huakita, e ai ki ēnei tapanga. I roto i te mimi waikawa, ka huri hei formaldehyde, e whakaahuatia ana e te tapanga hei mea whakamate huakita, hei mea aukati rānei i te tipu o te huakita. Nā taua tukanga e mārama ai te hiranga o te kaiwhakawaikawa. Ka āwhina te sodium phosphate monobasic ki te pupuri i te waikawatanga o te mimi kia wāwāhi ai te methenamine i runga i te tikanga e hiahiatia ana. Nō reira, ko ngā rongoā e whakapiki ana i te pH o te mimi, tae atu ki ētahi rongoā whakakore waikawa, ngā thiazide, me ngā kaiwhakakore waikawa o te mimi, ka taea te whakaiti i te pānga o te methenamine kua whakaahuatia i te tapanga.

He whāiti ake te mahi a te phenyl salicylate. E ai ki te tapanga, ka tuku tēnei i te salicylate, e whakaahuatia ana hei rongoā whakamāmā mamae āhua ngoikore. Kei roto tēnei i a Uribel me Uro-MP, ā, kāore i roto i te Urogesic Blue o nāianei. Ki te whakawhiti tētahi tūroro mai i te kāpene e rima ōna kai whakauru ki te pire e whā ōna kai whakauru, ā, ka kite kua iti iho te whakamāmā o te mamae, he rerekētanga mārama kei ngā tapanga hei kōrerorero ki te kaiwhakahaunga rongoā. Ehara tēnei i te mea ngaro.

He mahi tautoko tā te methylene blue i ēnei tapanga. E kī ana ngā tapanga pēnei i tō Uribel me te tapanga Urogesic Blue he patu moroiti ngoikore tēnei. He mea āta whiriwhiri taua kupu. Kāore e whakaahua ana i te methylene blue hei maimoatanga takitahi mō te pūnaha mimi, ā, kāore tētahi o ēnei tapanga e toru e kī ana ka taea te whakawhiti i te methylene blue anake me te rongoā whakakotahi. Ka tohu te tae kikorangi kei roto taua kai whakauru. Kāore te tae e ine ana i te pānga o ērā atu kai whakauru.

Ko te hyoscyamine sulfate te mea e whakarato ana i te mahi whakamāmā kōpīpī. E whakaahua ana te tapanga i tēnei hei aukati i te pūnaha io parasympathetic, e whakaiti ana i ngā tohu e pā ana ki te kōpīpī o te tōngāmimi. Mā aua āhuatanga rongoā anō e whakamārama ngā whakatūpato i te tapanga: te waha maroke, te tirohanga rehurehu, te whanoke, te hiamoe rānei, te tere o te kakapa, me te uaua ki te mimi, tae atu ki te pupuri mimi whakapeka. Ka tohutohu ngā tapanga i ngā tūroro kia mutu te tango rongoā, kia rapu hoki i te manaakitanga hauora mēnā ka tere te kakapa, ka whanoke, ka rehurehu rānei te tirohanga. Ka tautohu hoki i te papahewa, te aukatinga o te ara kūnatu, te myasthenia gravis, me te mate aukati o te pūnaha mimi hei āhuatanga me tino āwangawanga.

He aha e kore ai te methylene blue anake e noho hei whakakapi

Ki te tangohia ngā kai whakauru e whā i tētahi hua e rima ōna kai whakauru, kāore te waikano e toe ana e taea te pupuri i te rongoā whakakotahi kua whakaahuatia i te tapanga. Ka whakarato te methenamine i te mahi patu huakita mā te formaldehyde. Ka pupuri te phosphate i ngā āhuatanga waikawa e hiahiatia ana mō taua mahi. Ka whakarato te hyoscyamine i te pānga whakamāmā kōpīpī. I a Uribel me Uro-MP, ka whakarato te phenyl salicylate i te wāhanga whakamāmā mamae kua tohua ki te tapanga. Kāore he pānga o aua kai whakauru hoa i ēnei kaha i tētahi wairewa mā te kaihoko, kotahi noa tōna kai whakauru. Kāore hoki tētahi tapanga rongoā whakakotahi e tautoko ana i taua whakawhitinga.

Ka rerekē hoki te aromatawai haumaru ina whakaarohia te rongoā katoa. Kei ngā mōhiohio whakahaunga mō te methylene blue ka tukuna ki roto i te ia toto tētahi whakatūpato kua tāparetia mō te mate serotonin syndrome tino taumaha, tērā hoki ka mate ai te tangata, ina whakamahia me ngā rongoā e pā ana ki te serotonin me ngā opioid. Kāore taua whakatūpato kua tāparetia i ngā tapanga o ngā rongoā whakakotahi e toru mō te pūnaha mimi. E aro ana ō rātou wāhanga pāhekoheko ki ngā pānga aukati muscarinic, ngā pānga ki te pH o te mimi, te tūraru o te hanga tioata sulfonamide i te mimi i te taha o te formaldehyde, te kore e taea te whakamanawanui ki te salicylate, me ētahi take e pā ana. Ehara te korenga o taua whakatūpato i te whakaaetanga kia whakamahia tētahi rongoā whakakotahi kei roto te methylene blue me ngā rongoā mō te pāpōuri. Kāore anō kia tino mārama te tūraru e pā ana ki te serotonin ina whakamahia te methylene blue i ngā horopeta iti mā ngā ara kē atu i te ia toto. Nō reira, me tono te tangata e tango ana i tētahi SSRI, SNRI, MAOI, linezolid, dextromethorphan, bupropion, rongoā whakaongaonga, opioid rānei, kia arotakehia tuatahitia tana rārangi rongoā katoa e te kaiwhakahaunga me te kaitaka rongoā. Ka whakamārama tā mātou aratohu pāhekoheko mō te methylene blue i ngā take e hāngai ana ki te ara tuku rongoā, me ētahi atu taipitopito.

Kotahi te whārangi mō ngā momo waitohu, kaua ko te ingoa kotahi mō ngā pounamu katoa

Nā ngā rapunga mō ngā rongoā whānui e rite ana ki a Uribel ka puta te nuinga o te rangirua. Ko tētahi rongoā whānui e whakarārangi ana i aua kai whakauru e rima i te 118 mg, 40.8 mg, 36 mg, 10 mg, me te 0.12 mg, me noho ki te rārangi whakataurite kotahi me te Uribel whai waitohu. Kāore te ingoa o te kaihanga me te tae o te kāpene e tautuhi ana i te rongoā. Mā te rārangi kai whakauru e tautuhi.

Nā taua take anō ka noho a Uro-MP ki te rārangi kotahi. He ōrite tōna tapanga o nāianei ki te huinga kai whakauru e rima o Uribel, he ōrite hoki ngā kaha. Nō reira, mā te pupuri i ēnei ki te whārangi kotahi e ārai te wehewehenga hē o ēnei hanganga rongoā e rua, he tata tonu te ōrite. Me noho hoki a Urogesic Blue ki taua whārangi, engari ki tētahi rārangi kē, nā te mea kua whakarerekētia te hanganga o te pire o nāianei. E whā ōna kai whakauru, he 81.6 mg te methenamine me te 10.8 mg te methylene blue, ā, kāore he phenyl salicylate. Ki te kīia he ingoa ōrite ēnei ingoa e toru, ka ngaro taua rerekētanga. Mā ngā rangahau e pā ana ki ngā tohu o te pūnaha mimi e hono tonu tēnei whakataurite ki te pātai haumanu. Ka whakaatu hoki tā mātou tikanga pānui tapanga me pēhea te tirotiro i tētahi pounamu rongoā kua tukuna mā te whakataurite ki te ripanga o runga.

He mahanga anō kei ngā pounamu tawhito. Kua rerekē ngā hanganga rongoā e whakamahi ana i ēnei ingoa waitohu i roto i te wā, ā, kāore pea tētahi pire nō ngā tau kua pahure e ōrite ki te tapanga o nāianei. Kaua e whakamahi tonu i tētahi rārangi kai whakauru tawhito. Pānuitia te pounamu kei tō ringa.

Ina rerekē ngā tohu, whakaarohia te kai whakauru e hāngai ana

Ki te puta he rerekētanga i muri i te tīmata, i te whakawhiti rānei ki tētahi o ēnei hua, me kimi ko tēhea te take. He pānga motuhake tō ia kai whakauru, ā, ka āwhina te tapanga ki te tautohu i te kai whakauru e tika ana kia uiuitia.

Ki te iti iho te mamae wera engari ka mau tonu te hiahia ohorere ki te mimi me te kōpīpī, ka tohu tēnei ki te rerekētanga o te mahi whakamāmā mamae me te mahi whakamāmā kōpīpī. Ka hāngai te phenyl salicylate ki te mamae āhua māmā, ā, ka hāngai te hyoscyamine ki te kōpīpī. Ina whakawhiti ki a Urogesic Blue, ka kore te phenyl salicylate i te rongoā. Ki te mau tonu te mamae wera, me kōrerorero tika mō te wāhanga whakamāmā mamae kua kore, kaua e whakapiki noa i te horopeta o te pire hou.

Ki te puta hou te waha maroke, te rehurehu o te tirohanga ki ngā mea tata, te kōroke, te tere o te manawa, te uaua rānei ki te tīmata mimi, ka tohu ēnei ki te hyoscyamine. He pānga aukati muscarinic ēnei kua tuhia ki te tapanga, ā, ka hiahiatia pea he manaakitanga hauora ohotata mō te pupuri mimi. Kaua e ngana ki te whakatika i ēnei mā tētahi atu rongoā whakangā tōngāmimi me te kore tohutohu a te kaiwhakahaunga, nā te mea ka taea e ētahi atu rongoā aukati muscarinic te whakapiki i taua pānga.

Ki te puta te kōpukupuku kiri, te tangi i ngā taringa, te kore rānei e taea te whakamanawanui ki te rongoā i tētahi tangata e tairongo ana ki te aspirin, ka tohu ēnei ki te wāhanga salicylate o Uribel me Uro-MP. Ka kōrero ngā tapanga mō te tūponotanga o te kore e taea te whakamanawanui ki ngā rongoā whai pānga, i ngā tūroro kāore e taea te whakamanawanui ki ngā salicylate. Mā te kaiwhakahaunga e whakatau he kōwhiringa kāore he salicylate, kaua mā te tangata e whakawhiti ake, nā te mea kei roto tonu i te whakakapi te methenamine, te methylene blue, me te hyoscyamine, ā, he herenga anō tō ia mea.

Ko ngā pātai mō te matū o te mimi kāpuapua e hāngai ana ki te methenamine me te phosphate. Ka whakararu te mimi kawakore i te tukanga mahi a te methenamine kua tuhia ki te tapanga. Ka whakatūpato hoki ngā tapanga ka taea e ngā rongoā sulfonamide te hanga tōtā i te taha o te formaldehyde i roto i te mimi, me te whakapiki i te tūraru o te hanga tioata i te mimi. E whakaahua ana taua whakatūpato i tētahi pāhekoheko ki tētahi rongoā sulfonamide motuhake. Kāore e kī ana he paturopi sulfa kei roto i ēnei hua mō te pūnaha mimi. Kawea te rārangi rongoā katoa, tae atu ki ngā rongoā whakakore waikawa me ngā thiazide, ki te arotake. Ko ngā pātai mō te ahunga o te pokenga me te wā e tika ana kia maimoatia anō, e hāngai ana ki tā mātou ara manaakitanga mō te pokenga o te pūnaha mimi.

Kaua e whakapae he ōrite tētahi hua nō tāwāhi he ingoa āhua rite tōna

He rerekē ngā rongoā whakakotahi patu moroiti, whakamāmā mamae hoki mō te pūnaha mimi, i tēnā whenua, i tēnā whenua. Ko tētahi hua e hokona ana ki tāwāhi, he ingoa āhua rite tōna e pā ana ki te kikorangi, ki te methenamine rānei, tērā pea he rerekē ōna kai whakauru, ōna āhua tote, ōna kaha rānei i ngā tapanga US kua whakatauritea i konei. Ko te whakataurite pono anake ko te pepa mōhiohio kei te mōkihi, ko te whakarāpopototanga rānei o ngā āhuatanga o te hua, mō taua whenua me taua mōkihi tonu kua tukuna. Whakatauritea ngā tūnga e rima katoa o te ripanga: te methenamine, te āhua phosphate, te noho mai, te kore rānei o te phenyl salicylate, te kaha o te methylene blue, me te kaha o te hyoscyamine. Ki te iti iho i tēnā te whakataurite, he ōritenga kāwai noa, kāore he ōritenga kai whakauru. Ka kōrerotia ngā tauira whakaingoa puta noa i ngā rohe whenua i tā mātou whakataurite ā-ao mō ngā hua o te pūnaha mimi.

Kawea kia toru ngā mea ki te kaitaka rongoā: te pounamu rongoā kua tukuna, te rārangi katoa o ngā rongoā me ngā tāpiringa tae atu ki ngā matū e pā ana ki te serotonin me ngā rongoā whakakore waikawa, me te tohu kua rerekē. Mā aua mea e toru ka taea e te kaitaka rongoā te hono i te raruraru ki te kai whakauru nāna te pānga, kaua e hoki anō ki te tautohe mō te ingoa waitohu.